2D Materials: Fluorogenic 2D Peptidosheet Unravels CD47 as a Potential Biomarker for Profiling Hepatocellular Carcinoma and Cholangiocarcinoma Tissues (Adv. Mater. 5/2017)
Source abstract
Abstract
In article 1604253, X.-P. He, H.-Y. Wang, and co-workers describe supramolecular assembly between water-soluble 2D MoS2 and a peptide probe producing a 2D peptidosheet suited for the profiling of different carcinoma tissues over healthy tissues in clinical specimens. The dragon symbolizes the peptide ligand selective for CD47 on the surface of cancer tissues. The dragon is originally “hidden” in the 2D MoS2 materials, but once it detects cancer tissues, it is set free to shed light on the cancer, rather than normal tissues without CD47 expression, through releasing its fire (fluorescence).
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Supramolecular Self-Assembly in Materials · Advanced biosensing and bioanalysis techniques
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Affiliations
International Cooperation Laboratory on Signal Transduction Eastern Hepatobiliary Surgery Institute the Second Military Medical University Shanghai 200433 P. R. China
Key Laboratory for Advanced Materials & Institute of Fine Chemicals School of Chemistry and Molecular Engineering East China University of Science and Technology 130 Meilong Rd. Shanghai 200237 P. R. China
References
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