DataVXAdvanced MaterialsPaper
journal article·2016-12Open access

DNA Extraction: A Simple Thermoplastic Substrate Containing Hierarchical Silica Lamellae for High‐Molecular‐Weight DNA Extraction (Adv. Mater. 48/2016)

Ye Zhang, Yi Zhang, Jeffrey M. Burke, Kristin Gleitsman, Sarah M. Friedrich, Kelvin J. Liu, Tza‐Huei Wang

Advanced Materials· Volume 28· Issue 48
Publisher pageOpen full text
Source abstract

Abstract

K. J. Liu, T.-H. Wang and co-workers report a novel magnetic thermoplastic silica material called Nanobind on page 10630. Nanobind employs a jellyfish tentacle binding mechanism to perform high yield extraction of ultra high molecular weight genomic DNA. It is fabricated using an easily-scaled, heat-shrinking process to generate a high density of microscale folds and nanoscale silica lamellae that harbor DNA from shear force exposure and enable binding of vast amounts of reference quality DNA.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Diatoms and Algae Research · Mesoporous Materials and Catalysis · Microfluidic and Capillary Electrophoresis Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Biomedical Engineering Department Johns Hopkins University Baltimore MD 21218 USA

Institute of Bioengineering and Nanotechnology Agency of Science Technology and Research Singapore 138669 Singapore

Circulomics Inc Baltimore MD 21211 USA

Pacific Biosciences Inc Menlo Park CA 94025 94025 USA

Mechanical Engineering Department Johns Hopkins University Baltimore MD 21218 USA

Sidney Kimmel Comprehensive Cancer Center Johns Hopkins University Baltimore MD 21218 USA

Center of Cancer Nanotechnology Excellence Johns Hopkins University Baltimore MD 21218 USA

References

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