DataVXAdvanced MaterialsPaper
journal article·2013-01-11Open access

Gene Delivery: Plasmid‐Templated Shape Control of Condensed DNA–Block Copolymer Nanoparticles (Adv. Mater. 2/2013)

Xuan Jiang, Wei Qu, Deng Pan, Yong Ren, John‐Michael Williford, Honggang Cui, Erik Luijten, Hai‐Quan Mao

Advanced Materials· Volume 25· Issue 2
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Source abstract

Abstract

Micellar nanoparticles are created by Hai-Quan Mao, Erik Luijten, and co-workers on page 227 through complexation of plasmid DNA (green) and block copolymers (blue/brown). Variation of solvent polarity allows systematic control over the micelle shape (modeling images are shown in the foreground of the image and transmission electron microscopy images in the background) without changing their chemical composition, paving the way for targeted gene delivery.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: RNA Interference and Gene Delivery · Advanced biosensing and bioanalysis techniques

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