DataVXAdvanced MaterialsPaper
journal article·2018-06Open access

Nanohybrids: Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles, and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics (Adv. Mater. 24/2018)

Zehua Liu, Yunzhan Li, Wei Li, Chen Xiao, Dongfei Liu, Chao Dong, Ming Zhang, Ermei Mäkilä, Marianna Kemell, Jarno Salonen, Jouni T. Hirvonen, Hongbo Zhang, Dawang Zhou, Xianming Deng, Hélder A. Santos

Advanced Materials· Volume 30· Issue 24
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Source abstract

Abstract

A nanohybrid based on porous silicon (PSi) nanoparticles, gold nanoparticles, and acetalated dextran is designed for acute liver failure (ALF) reversal and CT-imaging-facilitated ALF indication. In article number 1703393, Hongbo Zhang, Dawang Zhou, Xianming Deng, Hélder A. Santos, and co-workers develop a PSi-based nanohybrid composite for liver regeneration and ALF treatment. This system is used to identify pathological changes in the tissues and selectively deliver drugs to these sites, facilitating imaging in vivo, and is thus a great potential theranostic platform for ALF.
Source: openalex_inverted_index · Quality: baseline

Research context

NanomaterialsComposites

OpenAlex topics: Liver Disease Diagnosis and Treatment · Neurological Disease Mechanisms and Treatments · Liver physiology and pathology

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Division of Pharmaceutical Chemistry and Technology Drug Research Program Faculty of Pharmacy University of Helsinki FI‐00014 Helsinki Finland

State Key Laboratory of Cellular Stress Biology Innovation Center for Cell Signaling, Network School of Life Sciences Xiamen University 361101 Fujian China

State‐Province Joint Engineering Laboratory of Targeted Drugs from Natural Products School of Life Sciences Xiamen University 361101 Fujian China

Helsinki Institute of Life Science (HiLIFE) University of Helsinki FI‐00014 Helsinki Finland

Laboratory of Industrial Physics Department of Physics University of Turku FI‐20014 Turku Finland

Department of Chemistry University of Helsinki FI‐00014 Helsinki Finland

Department of Pharmaceutical Science Åbo Akademi University FI‐20520 Turku Finland

Turku Center of Biotechnology Åbo Akademi University FI‐20520 Turku Finland

References

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