journal article·2017-05

Proteomics: New Opportunities and Challenges of Smart Polymers in Post‐Translational Modification Proteomics (Adv. Mater. 20/2017)

Guangyan Qing, Qi Lu, Yuting Xiong, Lei Zhang, Hongxi Wang, Xiuling Li, Xinmiao Liang, Taolei Sun

Advanced Materials· Volume 29· Issue 20
Publisher page

Abstract

Polymer-based phosphopeptide or glycopeptide enrichment materials are reviewed by Taolei Sun and co-workers in article number 1604670. In addition to high grafting densities and abundant binding sites, smart polymers display a dramatic conformational transition from globule to coil upon complexation with target peptides, enabling highly controllable binding/release behaviors of the peptides on material surfaces, which opens up a unique approach toward resolving the enrichment problems in post-translational modification proteomics.
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Research context

OpenAlex topics: Diatoms and Algae Research

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Affiliations

State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology 122 Luoshi Road Wuhan 430070 P. R. China

Institute of Biomedical and Pharmaceutical Sciences College of Bioengineering Hubei University of Technology 28 Nanli Road Wuhan 430068 P. R. China

Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical Physics Chinese Academy of Sciences 457 Zhongshan Road Dalian 116023 P. R. China

International School of Materials Science and Engineering Wuhan University of Technology 122 Luoshi Road Wuhan 430070 P. R. China

References

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