DataVXAdvanced MaterialsPaper
journal article·2012-05-22

Assays: Electrospun TiO2 Nanofiber‐Based Cell Capture Assay for Detecting Circulating Tumor Cells from Colorectal and Gastric Cancer Patients (Adv. Mater. 20/2012)

Nangang Zhang, Yuliang Deng, Qidong Tai, Boran Cheng, Libo Zhao, Qinglin Shen, Rongxiang He, Longye Hong, Wei Liu, Shishang Guo, Kan Liu, Hisan‐Rong Tseng, Bin Xiong, Xing‐Zhong Zhao

Advanced Materials· Volume 24· Issue 20
Publisher page
Source abstract

Abstract

A nanostructured platform combining an electrospun TiO2 nanofiber-deposited substrate and a cell-capture agent is created by S. S. Guo, K. Liu, H.-R. Tseng, B. Xiong, X.-Z. Zhao, and co-workers. The platform, described on page 2756, realizes the capture of significant amounts of circulating tumor cells. The enhanced local topographic interactions between the horizontally packed TiO2 nanofiber-deposited substrates and the extracellular matrix scaffolds, in addition to anti-EpCAM/EpCAM biological recognition, contributes to the significantly enhanced capture efficiency as compared to flat surfaces.
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Research context

Nanomaterials

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications

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References

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