MICROFLUIDICS: Synthesis of Size‐Tunable Polymeric Nanoparticles Enabled by 3D Hydrodynamic Flow Focusing in Single‐Layer Microchannels (Adv. Mater. 12/2011)

Robust microfluidic synthesis of polymer nanoparticles based on nanoprecipitation is reported by Omid C. Farokhzad, Rohit Karnik, and co-workers on p. H79. 3D hydrodynamic flow focusing, realized by constructing three sequential inlets for vertical focusing followed by a conventional cross junction for horizontal focusing, isolates the polymer precursors from the channelwalls, both vertically and horizontally.