journal article·2015-05Open access

Epilepsy Treatment: Controlling Epileptiform Activity with Organic Electronic Ion Pumps (Adv. Mater. 20/2015)

Adam Williamson, Jonathan Rivnay, Loïg Kergoat, Amanda Jonsson, Sahika Inal, Ilke Uguz, Marc Ferro, Anton Ivanov, Theresia Arbring Sjöström, Daniel T. Simon, Magnus Berggren, George G. Malliaras, Christophe Bernard

Advanced Materials· Volume 27· Issue 20

Abstract

Organic electronic ion pumps (OEIPs) convert electrical current into ionic current. When in contact with neural tissue, this ionic current can be used to control the activity of neural networks. G. G. Malliaras, C. Bernard, and co-workers develop an OEIP capable of delivering the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), as described on page 3138. The ability of the OEIP to locally suppress epileptiform activity in the mouse hippocampus is demonstrated.
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Research context

OpenAlex topics: Conducting polymers and applications · Electrochemical sensors and biosensors · Electrochemical Analysis and Applications

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Affiliations

Aix Marseille Université INS, UMR_S 1106 13005 Marseille France

Inserm UMR_S 1106 13005 Marseille France

Department of Bioelectronics Ecole Nationale Supérieure des Mines CMP‐EMSE, MOC 13541 Gardanne France

Laboratory of Organic Electronics Department of Science and Technology Linköping University 601 74 Norrköping Sweden

References

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