journal article·2017-02

Drug Therapy: An Amphiphilic Ruthenium Polymetallodrug for Combined Photodynamic Therapy and Photochemotherapy In Vivo (Adv. Mater. 6/2017)

Wen Sun, Shuyi Li, Bernhard Häupler, Juan Liu, Shubin Jin, Werner Steffen, Ulrich S. Schubert, Hans‐Jürgen Butt, Xing‐Jie Liang, Si Wu

Advanced Materials· Volume 29· Issue 6
Publisher page

Abstract

X.-J. Liang, S. Wu, and co-workers demonstrate a redlight-responsive Ru-containing block copolymer as a polymetallodrug for phototherapy in article 1603702. This block copolymer self-assembles into nanoparticles that can accumulate at the tumor sitet. Red-light irradiation induces release of the anticancer Ru complexes and generates cytotoxic 1O2, both of which inhibit the growth of cancer cell.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Photodynamic Therapy Research Studies

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Affiliations

Max Planck Institute for Polymer Research Ackermannweg 10 55128 Mainz Germany

Chinese Academy of Sciences (CAS) Center for Excellence in Nanoscience and CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology Chinese Academy of Sciences 100190 Beijing China

Laboratory of Organic and Macromolecular Chemistry (IOMC) Jena Center for Soft Matter (JCSM) Friedrich Schiller University Jena Humboldtstr. 10 07743 Jena Germany

References

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