journal article·2019-03Open access

Drug Delivery: Modular Metal–Organic Polyhedra Superassembly: From Molecular‐Level Design to Targeted Drug Delivery (Adv. Mater. 12/2019)

Wei Zhu, Jimin Guo, Yi Ju, Rita E. Serda, Jonas G. Croissant, Jin Shang, Eric Coker, Jacob Ongudi Agola, Qi‐Zhi Zhong, Yuan Ping, Frank Caruso, C. Jeffrey Brinker

Advanced Materials· Volume 31· Issue 12

Abstract

A novel and modular super-assembly approach combines the synergistic advantages of metal–organic cage super-assemblies (e.g., highly controlled architecture, high payloads of multiple cargos) and micelles (e.g., low inherent toxicity) for targeted drug delivery is presented by Wei Zhu, C. Jeffrey Brinker, and co-workers in article number 1806774. By modification of the targeting moieties, targeted drug delivery to cancer cells is realized.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Supramolecular Self-Assembly in Materials · Dendrimers and Hyperbranched Polymers · Electrospun Nanofibers in Biomedical Applications

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Affiliations

Center for Micro‐Engineered Materials Department of Chemical and Biological Engineering The University of New Mexico Albuquerque NM 87131 USA

ARC Centre of Excellence in Convergent Bio–Nano Science and Technology and The Department of Chemical Engineering The University of Melbourne Parkville Victoria 3010 Australia

Department of Internal Medicine Molecular Medicine The University of New Mexico Albuquerque NM 87131 USA

School of Energy and Environment City University of Hong Kong Tat Chee Avenue Kowloon Hong Kong SAR P. R. China

Sandia National Laboratories Applied Optical/Plasma Sciences P.O. Box 5800, MS 1411 Albuquerque NM 87185‐1411 USA

College of Pharmaceutical Sciences Zhejiang University Hangzhou 310058 P. R. China

References

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