journal article·2016-10Open access

Drug Delivery: Gd‐Hybridized Plasmonic Au‐Nanocomposites Enhanced Tumor‐Interior Drug Permeability in Multimodal Imaging‐Guided Therapy (Adv. Mater. 40/2016)

Jing Wang, Jing Liu, Ying Liu, Liming Wang, Mingjing Cao, Yinglu Ji, Xiaochun Wu, Yingying Xu, Bing Bai, Qing Miao, Chunying Chen, Yuliang Zhao

Advanced Materials· Volume 28· Issue 40

Abstract

On page 8950, Y. Zhao and co-workers propose an insightful and attractive strategy for enhanced pathological permeability and retention (EPPR) effect in drug delivery. They fabricated a new Gd-hybridized plasmonic gold nanocomposite and then used a novel strategy by plasmonic feature-based localized and on-off controlled photothermal properties to increase the transportation and permeability of the nanocomposite (loaded with imaging agents and drugs) in the tumor interior, achieving high-sensitive multimodal imaging and simultaneously improving the therapeutic efficacy.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Extracellular vesicles in disease · Advanced Nanomaterials in Catalysis

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Affiliations

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology (NCNST) No.11, 1st North Street, Zhongguancun Beijing 100190 China

CAS Key Laboratory of Standardization and Measurement for Nanotechnology NCNST No.11, 1st North Street, Zhongguancun Beijing 100190 China

References

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