DataVXAdvanced MaterialsPaper
journal article·2022-10

Transformable ECM Deprivation System Effectively Suppresses Renal Cell Carcinoma by Reversing Anoikis Resistance and Increasing Chemotherapy Sensitivity (Adv. Mater. 43/2022)

Lu Wang, Cong Li, Jiaqi Wang, Guang Yang, Yulin Lv, Bo Fu, Lingrui Jian, Jinpeng Ma, Jiaao Yu, Zongzheng Yang, Peng Wu, Guangbin Li, Xiao Liu, Zhijian Kang, Ziqi Wang, Lei Wang, Hao Wang, Wanhai Xu

Advanced Materials· Volume 34· Issue 43
Publisher page
Source abstract

Abstract

Renal Cell Carcinoma In article number 2203518, Ziqi Wang, Lei Wang, Hao Wang, Wanhai Xu, and co-workers report a transformable extracellular matrix (ECM) deprivation system (EDS) that targets fibronectin for depriving the ECM of renal cell carcinoma (RCC). The cage-like nanofibers formed by the EDS deprive the ECM of RCC cells, which efficaciously reverses anoikis resistance and ameliorates the RCC's cell-adhesion-mediated drug resistance (CAM-DR).
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Tissue Engineering and Regenerative Medicine

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Affiliations

NHC Key Laboratory of Molecular Probes and Targeted Diagnosis and Therapy Harbin Medical University Harbin 150001 China

Department of Urology The Fourth Hospital of Harbin Medical University Heilongjiang Key Laboratory of Scientific Research in Urology No. 37 Yi‐Yuan Street, Nangang District, Heilongjiang Province Harbin 150001 China

Department of Neurosurgery The First Affiliated Hospital of Harbin Medical University Harbin 150001 China

CAS Center for Excellence in Nanoscience CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology (NCNST) No. 11 Beiyitiao Zhongguancun Beijing 100190 China

References

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