Monolithic DNApatite: An Elastic Apatite with Sub‐Nanometer Scale Organo–Inorganic Structures
Source abstract
Abstract
Abstract Hydroxyapatite (HA) exhibits outstanding biocompatibility, bioactivity, osteoconductivity, and natural anti‐inflammatory properties. Pure HA, ion‐doped HA, and HA‐polymer composites are investigated, but critical limitations such as brittleness remain; numerous efforts are being made to address them. Herein, the novel self‐crystallization of a polymeric single‐stranded deoxyribonucleic acid (ssDNA) without additional phosphate ions for synthesizing deoxyribonucleic apatite (DNApatite) is presented. The synthesized DNApatite, DNA1Ca2.2(PO4)1.3OH2.1, has a repetitive dual phase of inorganic HA crystals and amorphous organic ssDNA at the sub‐nm scale, forming nanorods. Its mechanical properties, including toughness and elasticity, are significantly enhanced compared with those of HA nanorod, with a Young's modulus similar to that of natural bone.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Radioactive element chemistry and processing · Chemical Synthesis and Characterization
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Advanced Materials Science & Engineering Sungkyunkwan University (SKKU) Suwon 16419 Republic of Korea
Research Center for Advanced Materials Technology SKKU Suwon 16419 Republic of Korea
School of Biomedical Engineering Korea University Seoul 02841 Republic of Korea
School of Mechanical Engineering SKKU Suwon 16419 Republic of Korea
Analysis Center for Research Advancement Korea Advanced Institute of Science and Technology Daejeon 34141 Republic of Korea
Department of Energy Science SKKU Suwon 16419 Republic of Korea
Department of MetaBioHealth SKKU Suwon 16419 Republic of Korea
Funding
National Research Foundation of Korea · Ministry of Science and ICT, South Korea · Ministry of Education
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