Black Phosphorus: Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics (Adv. Mater. 1/2017)
Source abstract
Abstract
In article 1603276, J. Shi, H. Zhang, L. Mei, and co-workers describe black phosphorus nanosheets (BP NSs), which could lead to an enhanced antitumor effect, by a triple-response combined therapy strategy. When they enter the cancer cell, the BP NSs can produce a local high temperature initiated by an 808 nm laser. Release of loaded doxorubicin can be triggered by the laser and heat, leading to a combined photothermal–chemotherapy effect, which effectively kills the cancer cell. Moreover, under the influence of chloroquine, the degradation of BP NSs in the lysosome can be inhibited. The drug is then concentrated in the cell nucleus.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics
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Affiliations
Graduate School at Shenzhen Tsinghua University Shenzhen 518055 China
School of Life Sciences Tsinghua University Beijing 100084 China
Shenzhen Key Laboratory of Two‐Dimensional Materials and Devices (SKTMD) SZU‐NUS Collaborative Innovation Center for Optoelectronic Science and Technology, and Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province Shenzhen University Shenzhen 518060 China
Brigham and Women's Hospital Harvard Medical School 75 Francis Street Boston MA 02115 USA
References
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