journal article·2011-07-12

Direct Electrical Measurement of Protein–Water Interactions and Temperature Dependence Using Piezoelectric Microcantilevers

Jeong Hoon Lee, Kyo Seon Hwang, Dae Sung Yoon, Ji Yoon Kang, Sang Kyung Kim, Tae Song Kim

Advanced Materials· Volume 23· Issue 26
Publisher page

Abstract

A platform that provides a fundamental tool to understand protein behaviors by a simple real-time electrical readout is demonstrated. Observing the temperature dependence of protein activity as well as the humidity-sensitive protein activity of a prostate-specific antigen (PSA) monoclonal antibody receptor (MAbs), as well as PSA–MAbs receptor complexes, provides a stability curve for the protein and a humidity dependence of their activity.
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Research context

OpenAlex topics: Mechanical and Optical Resonators · Force Microscopy Techniques and Applications · Analytical Chemistry and Sensors

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