DataVXAdvanced MaterialsPaper
journal article·2018-07Open access

Cancer Therapy: Programmed Nanoparticle‐Loaded Nanoparticles for Deep‐Penetrating 3D Cancer Therapy (Adv. Mater. 29/2018)

Jinhwan Kim, Changshin Jo, Won‐Gwang Lim, Sungjin Jung, Yeong Mi Lee, Jun Lim, Haeshin Lee, Jinwoo Lee, Won Jong Kim

Advanced Materials· Volume 30· Issue 29
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Source abstract

Abstract

In article number 1707557, Jinwoo Lee, Won Jong Kim, and co-workers demonstrate nanoparticle-loaded nanoparticles comprising large-pored silica nanoparticles and gold nanoparticles operated by functional DNA. Depending on the pH gradient in the cancer microenvironment, an elaborately programmed DNA transition induces dynamic behavior of the nanoparticle-loaded nanoparticle with three stages: preferential accumulation in cancerous region, deep penetration into the 3D cancer tissue, and intracellular specific anticancer drug release.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis

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Affiliations

Department of Chemistry Pohang University of Science and Technology (POSTECH) and Center for Self‐assembly and Complexity Institute for Basic Sciecne (IBS) Pohang 37673 Korea

Department of Chemical Engineering and School of Environmental Science and Engineering POSTECH Pohang 37673 Korea

School of Interdisciplinary Bioscience and Bioengineering POSTECH Pohang 37673 Korea

Beamline Division Pohang Light Source Pohang 37673 Korea

Department of Chemistry Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Korea

References

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