DataVXAdvanced MaterialsPaper
journal article·2016-04Open access

Multigrowth Factor Delivery via Immobilization of Gene Therapy Vectors

Jie Hao, Kenneth C. K. Cheng, Laura G. Kruger, Lena Larsson, James V. Sugai, Joerg Lahann, William V. Giannobile

Advanced Materials· Volume 28· Issue 16
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Source abstract

Abstract

Molecules can be immobilized onto biomaterials by a chemical vapor deposition (CVD) coating strategy. Pentafluorophenolester groups react with amine side chains on antibodies, which can selectively immobilize adenoviral vectors for gene delivery of growth factors. These vectors can produce functional proteins within defined regions of biomaterials to produce customizable structures for targeted tissue regeneration. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Research context

BiomaterialsMaterials processing

OpenAlex topics: 3D Printing in Biomedical Research · Nanofabrication and Lithography Techniques · Electrospun Nanofibers in Biomedical Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Periodontics and Oral Medicine School of Dentistry University of Michigan 1011 North University Avenue Ann Arbor MI 48109‐1078 USA

Biointerfaces Institute Department of Materials Science and Engineering B26‐115S NCRC University of Michigan 2800 Plymouth Road Ann Arbor MI 48109‐2800 USA

Department of Periodontology Institute of Odontology Medicinaregatan 12F 6th Floor University of Gothenburg SE‐405 30 Gothenburg Sweden

Biointerfaces Institute Department of Chemical Engineering Materials Science and Engineering Biomedical Engineering Macromolecular Science and Engineering B10‐A175 NCRC University of Michigan 2800 Plymouth Road Ann Arbor MI 48109‐2800 USA

Department of Periodontics and Oral Medicine and Department of Biomedical Engineering University of Michigan 1011 North University Avenue Ann Arbor MI 48109‐1078 USA

Funding

NIH

References (23)

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