DataVXAdvanced MaterialsPaper
journal article·2016-02Open access

Suspended Planar‐Array Chips for Molecular Multiplexing at the Microscale

Núria Torras, Juan Pablo Agusil, Patricia Vázquez, Marta Duch, Alberto M. Hernández‐Pinto, Josep Samitier, Enrique J. de la Rosa, Jaume Esteve, Teresa Suárez, Lluïsa Pérez‐García, José A. Plaza

Advanced Materials· Volume 28· Issue 7
Publisher pageOpen full text
Source abstract

Abstract

A novel suspended planar-array chips technology is described, which effectively allows molecular multiplexing using a single suspended chip to analyze extraordinarily small volumes. The suspended chips are fabricated by combining silicon-based technology and polymer-pen lithography, obtaining increased molecular pattern flexibility, and improving miniaturization and parallel production. The chip miniaturization is so dramatic that it permits the intracellular analysis of living cells.
Source: europepmc · Quality: candidate unverified · Source record ↗

Research context

Polymers

OpenAlex topics: Microfluidic and Capillary Electrophoresis Applications · Microfluidic and Bio-sensing Technologies · Biosensors and Analytical Detection

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Instituto de Microelectrónica de Barcelona IMB‐CNM (CSIC) C/dels Til·lers, Campus UAB Cerdanyola del Vallès Barcelona 08193 Spain

Nanobioengineering Group Institute for Bioengineering of Catalonia (IBEC) C/Baldiri i Reixac 15–21 Barcelona 08028 Spain

Centro de Investigaciones Biológicas, CIB (CSIC) C/Ramiro de Maeztu 9 Madrid 28040 Spain

Department d'Electrònica Universitat de Barcelona C/Martí i Franquès 1 Barcelona 08028 Spain

Centro de Investigación Biomédica en Red en Bioingeniería Biomateriales y Nanomedicina (CIBER‐BBN) C/María de Luna 11 Edificio CEEI Zaragoza 50018 Spain

Departament de Farmacologia i Química Terapèutica Institut de Nanociència i Nanotecnologia (IN2UB) Universitat de Barcelona Av. Joan XXIII s/n Barcelona 08028 Spain

Funding

Spanish Government

References (34)

Show source-provided references
1. 10.1038/nrd200610.1038/nrd2006 ↗
2. 10.1038/7444210.1038/74442 ↗
3. 10.1038/nrg161810.1038/nrg1618 ↗
4. 10.1126/science.289.5485.176010.1126/science.289.5485.1760 ↗
5. 10.1016/S1535-6108(03)00086-210.1016/S1535-6108(03)00086-2 ↗
6. 10.1038/nmat283610.1038/nmat2836 ↗
7. 10.1016/S0167-7799(01)01844-310.1016/S0167-7799(01)01844-3 ↗
8. 10.1038/nrd81710.1038/nrd817 ↗
9. 10.1038/nmat161710.1038/nmat1617 ↗
10. 10.1126/science.113492910.1126/science.1134929 ↗
11. 10.1038/nmat281510.1038/nmat2815 ↗
12. 10.1002/smll.20140160010.1002/smll.201401600 ↗
13. 10.1038/480133a10.1038/480133a ↗
14. 10.1038/nbt.264210.1038/nbt.2642 ↗
15. 10.1002/smll.20090130610.1002/smll.200901306 ↗
16. 10.1146/annurev.bioeng.10.061807.16050210.1146/annurev.bioeng.10.061807.160502 ↗
17. 10.1021/nl049350010.1021/nl0493500 ↗
18. 10.1002/ange.20131072710.1002/ange.201310727 ↗
19. 10.1002/anie.20131072710.1002/anie.201310727 ↗
20. 10.1002/adma.20110256010.1002/adma.201102560 ↗
21. 10.1038/nmat393810.1038/nmat3938 ↗
22. 10.1002/adma.20090409410.1002/adma.200904094 ↗
23. 10.1002/smll.20090073310.1002/smll.200900733 ↗
24. 10.1038/nnano.2013.11810.1038/nnano.2013.118 ↗
25. 10.1002/nbm.117310.1002/nbm.1173 ↗
26. 10.1002/smll.20090104110.1002/smll.200901041 ↗
27. 10.1126/science.116219310.1126/science.1162193 ↗
28. 10.1021/nl904200t10.1021/nl904200t ↗
29. 10.1038/nchem.25810.1038/nchem.258 ↗
30. 10.1002/adhm.20120021410.1002/adhm.201200214 ↗
31. 10.1039/b926690a10.1039/b926690a ↗
32. 10.1038/nprot.2013.15910.1038/nprot.2013.159 ↗
33. 10.1002/smll.20090153810.1002/smll.200901538 ↗
34. 10.1038/nmat194910.1038/nmat1949 ↗