journal article·2010-03-26

Engineering a Material Surface for Drug Delivery and Imaging using Layer‐by‐Layer Assembly of Functionalized Nanoparticles

Thomas Soike, Amanda K. Streff, Chenxia Guan, Ryan Ortega, Mohammed Tantawy, Christopher Pino, V. Prasad Shastri

Advanced Materials· Volume 22· Issue 12
Publisher page

Abstract

Layer-by-layer (LBL) assembly of functionalized nanoparticles (FNPs) within a polyelectrolyte network is described (see image). The LBL-NP-assembly-based modification can be used to engineer surfaces with multiple functions such as controlled (multiple-) drug release with distinct release kinetics and enhanced contrast in clinical imaging modalities. This novel surface modification strategy is expected to accelerate the development of bioresponsive coatings for implantable biomedical devices.
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Research context

OpenAlex topics: Polymer Surface Interaction Studies · Nanofabrication and Lithography Techniques · Hydrogels: synthesis, properties, applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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