journal article·2007-10-19

Calcium‐Doped Organosilicate Nanoparticles as Gene Delivery Vehicles for Bone Cells

S. Moudgil, J. Y. Ying

Advanced Materials· Volume 19· Issue 20
Publisher page

Abstract

Calcium-doped organosilicate nanoparticles for gene delivery are prepared by using a surfactant-mediated sol-gel synthesis. The enhanced uptake of these nanoparticles by osteoblast cells (see figure) makes them promising candidates for the transfection of bone cells. The complexes of Ca-SiO2 nanoparticles with DNA transfect bone cells effectively without inducing cytotoxicity in vitro.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Bone Tissue Engineering Materials · RNA Interference and Gene Delivery · Advanced biosensing and bioanalysis techniques

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