Tunable Release of Proteins with Polymer–Inorganic Nanocomposite Microspheres

Polymer–inorganic nanocomposite microspheres synthesized by a simple solid-in-oil-in-water emulsion technique can provide both sustained protein release with tunable gradient, and delayed protein release with tunable lag time. Microspheres with a tunable lag time between 2 and 6 weeks (see figure) can be used as delayed release vehicles for the sequential delivery of multiple proteins. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.