One‐step preparation of double‐walled microspheres
Source abstract
Abstract
Multilayered microspheres for drug delivery can be produced by several methods, but most techniques involve several stages and often lead to layers of non‐uniform thickness. The solcent evaporation method of producing double‐layered microspheres described here svoids these difficulties, a single step yielding micrespheres consisting of an inner core of polymer surrounded by a second polymer. The theory is presented and the characterization of the microspheres discussed.
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Research context
OpenAlex topics: Advanced Drug Delivery Systems · 3D Printing in Biomedical Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (17)
Show source-provided references
1. M. N.Vrancken US Patent 3 523 906 1970.
2. M.Morishita US Patent 3 960 757 1976.
3. Mathiowitz E. · J. Scanning Microsc. · 1990 · 4 · 329
4. 10.1002/app.1988.07035031610.1002/app.1988.070350316 ↗
5. 10.1016/0032-3861(90)90401-J10.1016/0032-3861(90)90401-J ↗
6. 10.1002/app.1992.07045011510.1002/app.1992.070450115 ↗
7. 10.3109/0363904780905564110.3109/03639047809055641 ↗
8. 10.1002/jps.260061100810.1002/jps.2600611008 ↗
9. E. N.Heistand J. G.Wagner E. L.Knoechel US Patent 24899 1960.
10. B. K.Green L.Schleicher(National Cash Register Company) US Patent 2800 458 1963.
11. E.Mathiowitz R.Langer US Patent 4 861 627 1989.
12. 10.1038/367258a010.1038/367258a0 ↗
13. Parrot E. L. · 1970
14. W. D.Harkin The Physical Chemistry of Surface Films Reinhold York1952.
15. S. Y.Hobbs M. E. J.Dekkers V. H.Watkins Polymer1988 1598.10.1016/0032-3861(88)90269-8 ↗
16. 10.1016/0021-9797(70)90073-110.1016/0021-9797(70)90073-1 ↗
17. A low‐viscosity acrylic available from Sigma Chemical Company.