journal article·2023-10Open access

Mechanical Signal‐Tailored Hydrogel Microspheres Recruit and Train Stem Cells for Precise Differentiation (Adv. Mater. 40/2023)

Zehao Chen, Zhendong Lv, Yaping Zhuang, Qimanguli Saiding, Wu Yang, Wei Xiong, Zhen Zhang, Hao Chen, Wenguo Cui, Yuhui Zhang

Advanced Materials· Volume 35· Issue 40

Abstract

Tissue Regeneration In article number 2300180, Hao Chen, Wenguo Cui, Yuhui Zhang, and co-workers propose a hydrogel-microsphere-based synthetic niche with cell recruiting and targeted cell differentiation properties via mechanotransduction. The microsphere niche guides the fate of endogenous stem cells in the aberrant mechanical microenvironment, offering an effective strategy for enhancing the endogenous regeneration of degenerated tissues.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Silk-based biomaterials and applications · Tissue Engineering and Regenerative Medicine

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Spine Surgery Renji Hospital Shanghai Jiao Tong University School of Medicine 160 Pujian Road Shanghai 200127 P. R. China

Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China

School of Mechatronic Engineering and Automation Shanghai University Nanchen Road 333 Shanghai 200444 P. R. China

References

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