Living Synthelectronics: A New Era for Bioelectronics Powered by Synthetic Biology
Source abstract
Abstract
Abstract Bioelectronics, which converges biology and electronics, has attracted great attention due to their vital applications in human–machine interfaces. While traditional bioelectronic devices utilize nonliving organic and/or inorganic materials to achieve flexibility and stretchability, a biological mismatch is often encountered because human tissues are characterized not only by softness and stretchability but also by biodynamic and adaptive properties. Recently, a notable paradigm shift has emerged in bioelectronics, where living cells, and even viruses, modified via gene editing within synthetic biology, are used as core components in a new hybrid electronics paradigm. These devices are defined as “living synthelectronics,” and they offer enhanced potential for interfacing with human tissues at informational and substance exchange levels. In this Perspective, the recent advances in living synthelectronics are summarized. First, opportunities brought to electronics by synthetic biology are briefly introduced. Then, strategic approaches to designing and making electronic devices using living cells/viruses as the building blocks, sensing components, or power sources are reviewed. Finally, the challenges faced by living synthelectronics are raised. It is believed that this paradigm shift will significantly contribute to the real integration of bioelectronics with human tissues.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Neuroscience and Neural Engineering · Modular Robots and Swarm Intelligence · Molecular Communication and Nanonetworks
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Soft Bio‐interface Electronics Lab Center of Neural Engineering CAS Key Laboratory of Human‐Machine Intelligence‐Synergy Systems Shenzhen Institute of Artificial Intelligence and Robotics for Society Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China
MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage National and Local Joint Engineering Laboratory for Synthesis Transformation and Separation of Extreme Environmental Nutrients School of Chemistry and Chemical Engineering Harbin Institute of Technology Harbin 150001 P. R. China
Key Laboratory of Quantitative Synthetic Biology Shenzhen Institute of Synthetic Biology Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China
School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore
Standard Robots Co.,Ltd，Room 405, Building D, Huafeng International Robot Fusen Industrial Park, Hangcheng Avenue, Guxing Community Xixiang Street, Baoan District Shenzhen 518055 China
Funding
National Natural Science Foundation of China · National Key Scientific Instrument and Equipment Development Projects of China · Shenzhen Science and Technology Innovation Program · Key Technologies Research and Development Program
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