journal article·2024-08

Bias‐Free Cardiac Monitoring Capsule

Xuecheng Qu, Sijing Cheng, Ying Liu, Yiran Hu, Yizhu Shan, Ruizeng Luo, Sixian Weng, Hui Li, Hongxia Niu, Min Gu, Yubo Fan, Bojing Shi, Zhuo Liu, Wei Hua, Zhou Li, Zhong Lin Wang

Advanced Materials· Volume 36· Issue 33
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Abstract

Abstract Cardiovascular disease (CVD) remains the leading cause of death worldwide. Patients often fail to recognize the early signs of CVDs, which display irregularities in cardiac contractility and may ultimately lead to heart failure. Therefore, continuously monitoring the abnormal changes in cardiac contractility may represent a novel approach to long‐term CVD surveillance. Here, a zero‐power consumption and implantable bias‐free cardiac monitoring capsule (BCMC) is introduced based on the triboelectric effect for cardiac contractility monitoring in situ. The output performance of BCMC is improved over 10 times with nanoparticle self‐adsorption method. This device can be implanted into the right ventricle of swine using catheter intervention to detect the change of cardiac contractility and the corresponding CVDs. The physiological signals can be wirelessly transmitted to a mobile terminal for analysis through the acquisition and transmission module. This work contributes to a new option for precise monitoring and early diagnosis of CVDs.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Muscle activation and electromyography studies · Electrospun Nanofibers in Biomedical Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Beijing Key Laboratory of Micro‐Nano Energy and Sensor Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences Beijing 101400 China

State Key Laboratory of Tribology in Advanced Equipment Department of Mechanical Engineering Tsinghua University Beijing 100084 China

The Cardiac Arrhythmia Center State Key Laboratory of Cardiovascular Disease National Clinical Research Center of Cardiovascular Diseases Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China

Department of Cardiology and Macrovascular Disease Beijing Tiantan Hospital Capital Medical University Beijing 100070 China

School of Nanoscience and Technology University of Chinese Academy of Sciences Beijing 100049 China

Department of Ultrasound State Key Laboratory of Cardiovascular Disease National Clinical Research Center of Cardiovascular Diseases Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China

Key Laboratory of Biomechanics and Mechanobiology Ministry of Education Beijing Advanced Innovation Center for Biomedical Engineering School of Engineering Medicine Beihang University Beijing 100191 China

Georgia Institute of Technology Atlanta GA 30332‐0245 USA

Funding

National Key Research and Development Program of China · National Natural Science Foundation of China · Chinese Academy of Medical Sciences · China Postdoctoral Science Foundation · Beijing Municipal Natural Science Foundation

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