Soft, Long‐Lived, Bioresorbable Electronic Surgical Mesh with Wireless Pressure Monitor and On‐Demand Drug Delivery
Source abstract
Abstract
Abstract Current research in the area of surgical mesh implants is somewhat limited to traditional designs and synthesis of various mesh materials, whereas meshes with multiple functions may be an effective approach to address long‐standing challenges including postoperative complications. Herein, a bioresorbable electronic surgical mesh is presented that offers high mechanical strength over extended timeframes, wireless post‐operative pressure monitoring, and on‐demand drug delivery for the restoration of tissue structure and function. The study of materials and mesh layouts provides a wide range of tunability of mechanical and biochemical properties. Dissolvable dielectric composite with porous structure in a pyramidal shape enhances sensitivity of a wireless capacitive pressure sensor, and resistive microheaters integrated with inductive coils provide thermo‐responsive drug delivery system for an antibacterial agent. In vivo evaluations demonstrate reliable, long‐lived operation, and effective treatment for abdominal hernia defects, by clear evidence of suppressed complications such as adhesion formation and infections.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Hernia repair and management · Hydrogels: synthesis, properties, applications · Electrospun Nanofibers in Biomedical Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
KU‐KIST Graduate School of Converging Science and Technology Korea University 145 Anam‐ro, Seongbuk‐gu Seoul 02841 Republic of Korea
SK Hynix Co., Ltd. 2091, Gyeongchung‐daero, Bubal‐eup Incheon Gyeonggi‐do 17336 Republic of Korea
Department of Pediatric Surgery Seoul National University Hospital 101, Daehak‐ro, Jongno‐gu Seoul 03080 Republic of Korea
Hanwha Systems Co., Ltd. 188, Pangyoyeok‐Ro, Bundang‐Gu Seongnam‐si Gyeonggi‐do 13524 Republic of Korea
Department of Electrical and Computer Engineering North Carolina State University Raleigh NC 27606 USA
Center for Advanced Self‐Powered Systems of Integrated Sensors and Technologies (ASSIST) North Carolina State University Raleigh NC 27606 USA
Department of Integrative Energy Engineering Korea University 145 Anam‐ro, Seongbuk‐gu Seoul 02841 Republic of Korea
Center for Biomaterials Biomedical Research Institute Korea Institute of Science and Technology (KIST) 5 Hwarang‐ro 14‐gil, Seongbuk‐gu Seoul 02792 Republic of Korea
Funding
Korea Institute of Science and Technology
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