journal article·2024-09

Jellyfish‐Inspired Artificial Spider Silk for Luminous Surgical Sutures

Kai Wen, Chao Zhang, Guanghao Zhang, Meilin Wang, Guangkai Mei, Zhenzhen Zhang, Weiqiang Zhao, Wenjin Guo, Qiang Zhou, Enzhao Liu, Yutian Zhu, Jie Bai, Meifang Zhu, Wei Wang, Zunfeng Liu, Xiang Zhou

Advanced Materials· Volume 36· Issue 36
Publisher page

Abstract

Abstract The development of functional surgical sutures with excellent mechanical properties, good fluorescence, and high cytocompatibility is highly required in the field of medical surgeries. Achieving fibers that simultaneously exhibit high mechanical robustness, good spinnability, and durable fluorescence emission has remained challenging up to now. Taking inspiration from the spinning process of spider silk and the luminescence mechanism of jellyfish, this work reports a luminous artificial spider silk prepared with the aim of balancing the fiber spinnability and mechanical robustness. This is realized by employing highly hydrated segments with aggregation‐induced luminescence for enhancing the fiber spinnability and polyhydroxyl segments for increasing the fiber mechanical robustness. Twist insertion during fiber spinning improves the fiber strength, toughness, and fluorescence emission. Furthermore, coating the fiber with an additional polymer layer results in a “sheath–core” architecture with improved mechanical properties and capacity to withstand water. This work provides a new design strategy for performing luminescent and robust surgical sutures.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Silk-based biomaterials and applications · Electrospun Nanofibers in Biomedical Applications · Corneal Surgery and Treatments

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory of Medicinal Chemical Biology Key Laboratory of Functional Polymer Materials Tianjin Key Laboratory of Functional Polymer Materials College of Chemistry Nankai University Tianjin 300071 China

Department of Science School of Traditional Chinese Pharmacy China Pharmaceutical University Nanjing 211198 China

College of Chemical Engineering Inner Mongolia University of Technology Hohhot 010051 China

Institute of Veterinary Medicine Jiangsu Academy of Agricultural Sciences Nanjing 210014 China

Department of Orthopaedics, Tianjin First Central Hospital Nankai University Tianjin 300071 China

Tianjin Key Laboratory of Ionic‐Molecular Function of Cardiovascular Disease Department of Cardiology Tianjin Institute of Cardiology the Second Hospital of Tianjin Medical University Tianjin 300211 China

College of Materials Chemistry and Chemical Engineering Hangzhou Normal University Hangzhou 311121 China

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and Engineering Donghua University Shanghai 201620 China

Funding

National Key Research and Development Program of China · National Natural Science Foundation of China · Fundamental Research Funds for the Central Universities

References (70)

Show source-provided references
1. 10.1002/adma.20200473310.1002/adma.202004733 ↗
2. 10.1126/sciadv.abc301210.1126/sciadv.abc3012 ↗
3. 10.1016/j.onano.2022.10012010.1016/j.onano.2022.100120 ↗
4. 10.1073/pnas.110495410810.1073/pnas.1104954108 ↗
5. 10.3389/fmats.2020.0005010.3389/fmats.2020.00050 ↗
6. 10.1002/anie.20201559210.1002/anie.202015592 ↗
7. 10.7150/ijms.1972710.7150/ijms.19727 ↗
8. 10.1016/j.arth.2013.09.04510.1016/j.arth.2013.09.045 ↗
9. 10.1039/b915574k10.1039/b915574k ↗
10. 10.1002/adma.20240604710.1002/adma.202406047 ↗
11. 10.1038/s41551-021-00796-910.1038/s41551-021-00796-9 ↗
12. 10.1126/science.aaw868210.1126/science.aaw8682 ↗
13. 10.1016/j.biomaterials.2020.12025410.1016/j.biomaterials.2020.120254 ↗
14. 10.1016/j.addr.2018.07.01410.1016/j.addr.2018.07.014 ↗
15. 10.1007/s40820-023-01187-210.1007/s40820-023-01187-2 ↗
16. 10.1002/adma.20180208410.1002/adma.201802084 ↗
17. 10.1038/s41569-020-0426-410.1038/s41569-020-0426-4 ↗
18. 10.1038/s41591-021-01279-910.1038/s41591-021-01279-9 ↗
19. 10.1021/acsbiomaterials.2c0032210.1021/acsbiomaterials.2c00322 ↗
20. 10.1002/slct.20180034210.1002/slct.201800342 ↗
21. 10.1002/advs.20160048010.1002/advs.201600480 ↗
22. 10.1002/adhm.20190155210.1002/adhm.201901552 ↗
23. 10.1021/acsbiomaterials.0c0130810.1021/acsbiomaterials.0c01308 ↗
24. 10.1038/s41467-020-17167-810.1038/s41467-020-17167-8 ↗
25. 10.1038/3506900010.1038/35069000 ↗
26. 10.1038/s41467-019-13257-410.1038/s41467-019-13257-4 ↗
27. 10.1002/adma.20220184310.1002/adma.202201843 ↗
28. 10.1002/adma.20221211210.1002/adma.202212112 ↗
29. 10.3866/PKU.WHXB20220405910.3866/PKU.WHXB202204059 ↗
30. 10.1073/pnas.170538011410.1073/pnas.1705380114 ↗
31. 10.1002/adma.20230087610.1002/adma.202300876 ↗
32. 10.1002/adma.20190431110.1002/adma.201904311 ↗
33. 10.1002/adma.20210149810.1002/adma.202101498 ↗
34. 10.1038/s41467-022-29773-910.1038/s41467-022-29773-9 ↗
35. 10.1002/adma.20230044710.1002/adma.202300447 ↗
36. 10.1021/nl101341w10.1021/nl101341w ↗
37. 10.1039/c1cs15113d10.1039/c1cs15113d ↗
38. 10.1039/D1MH01172C10.1039/D1MH01172C ↗
39. 10.1021/acsmacrolett.2c0000210.1021/acsmacrolett.2c00002 ↗
40. 10.1021/acsnano.1c0272010.1021/acsnano.1c02720 ↗
41. 10.1016/j.cej.2020.12679310.1016/j.cej.2020.126793 ↗
42. 10.1016/j.matt.2022.08.02810.1016/j.matt.2022.08.028 ↗
43. 10.1002/adfm.20231313110.1002/adfm.202313131 ↗
44. 10.1002/adhm.20150000210.1002/adhm.201500002 ↗
45. 10.1016/j.biomaterials.2017.08.00310.1016/j.biomaterials.2017.08.003 ↗
46. 10.1039/C9TC03461G10.1039/C9TC03461G ↗
47. 10.1126/sciadv.160095510.1126/sciadv.1600955 ↗
48. 10.1039/D1TC03403K10.1039/D1TC03403K ↗
49. 10.1021/acsami.1c1723210.1021/acsami.1c17232 ↗
50. 10.1002/smll.20200520510.1002/smll.202005205 ↗
51. 10.1021/acsbiomaterials.8b0098610.1021/acsbiomaterials.8b00986 ↗
52. 10.1007/s40820-019-0303-z10.1007/s40820-019-0303-z ↗
53. 10.1021/acsbiomaterials.9b0020010.1021/acsbiomaterials.9b00200 ↗
54. 10.1002/adfm.20230607110.1002/adfm.202306071 ↗
55. 10.1016/j.zool.2011.02.00110.1016/j.zool.2011.02.001 ↗
56. 10.1002/adma.20170716910.1002/adma.201707169 ↗
57. 10.1002/adma.20210468110.1002/adma.202104681 ↗
58. 10.1038/nmat153410.1038/nmat1534 ↗
59. 10.1021/jacs.0c0969110.1021/jacs.0c09691 ↗
60. 10.1021/ja806962e10.1021/ja806962e ↗
61. 10.1038/s41467-019-09218-610.1038/s41467-019-09218-6 ↗
62. 10.1021/jacs.2c1326410.1021/jacs.2c13264 ↗
63. 10.1016/j.mattod.2019.08.01010.1016/j.mattod.2019.08.010 ↗
64. 10.1371/journal.pone.000099810.1371/journal.pone.0000998 ↗
65. 10.1039/B813273A10.1039/B813273A ↗
66. 10.1038/s41551-021-00802-010.1038/s41551-021-00802-0 ↗
67. 10.1016/j.intimp.2021.10759810.1016/j.intimp.2021.107598 ↗
68. 10.1038/nri186210.1038/nri1862 ↗
69. 10.4049/jimmunol.168.10.527810.4049/jimmunol.168.10.5278 ↗
70. 10.1038/cmi.2017.13410.1038/cmi.2017.134 ↗