Enzyme Therapeutic for Ischemia and Reperfusion Injury in Organ Transplantation
Source abstract
Abstract
Abstract Ischemia–reperfusion injury (IRI) remains as a critical challenge for organ transplantation. Herein, an enzyme therapeutic based on superoxide dismutase and catalase for effective mitigation of IRI and pathogen‐induced liver injury is reported, providing a therapeutic for organ transplantation and other diseases.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Heme Oxygenase-1 and Carbon Monoxide · Acute Kidney Injury Research · Cardiac Ischemia and Reperfusion
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
College of Biotechnology and Pharmaceutical Engineering Nanjing Tech University Nanjing 211816 China
Department of Chemical and Biomolecular Engineering University of California, Los Angeles Los Angeles CA 90095 USA
Department of Microbiology Immunology and Molecular Genetics David Geffen School of Medicine UCLA AIDS Institute University of California, Los Angeles Los Angeles CA 90095 USA
Beijing Advanced Innovation Center for Soft Matter Science and Engineering College of Life Science and Technology Beijing University of Chemical Technology Beijing 100029 China
References (68)
Show source-provided references
1. 10.1002/lt.2574210.1002/lt.25742 ↗
2. “Organ Donation and Transplantation Statistics: Graph Data ”https://www.organdonor.gov/statistics-stories/statistics/data.html(accessed:2020).
3. 10.1111/liv.1409110.1111/liv.14091 ↗
4. 10.1016/S0002-9610(00)00573-010.1016/S0002-9610(00)00573-0 ↗
5. 10.1038/nrgastro.2012.22510.1038/nrgastro.2012.225 ↗
6. 10.1111/j.1600-6143.2011.03579.x10.1111/j.1600-6143.2011.03579.x ↗
7. 10.7150/thno.3883410.7150/thno.38834 ↗
8. 10.1155/2012/32963510.1155/2012/329635 ↗
9. 10.1196/annals.1427.01510.1196/annals.1427.015 ↗
10. 10.3389/fbioe.2021.75201910.3389/fbioe.2021.752019 ↗
11. Zhong X. · Mol. Med. Rep. · 2019 · 20 · 2101
12. 10.1002/hep.2595810.1002/hep.25958 ↗
13. 10.1038/nm157710.1038/nm1577 ↗
14. 10.1016/j.jss.2009.08.00510.1016/j.jss.2009.08.005 ↗
15. 10.1126/science.283482110.1126/science.2834821 ↗
16. 10.1161/hyp.38.4.87710.1161/hyp.38.4.877 ↗
17. 10.3389/fphar.2017.0003110.3389/fphar.2017.00031 ↗
18. 10.1155/2020/508387610.1155/2020/5083876 ↗
19. 10.1089/15230860130018517910.1089/152308601300185179 ↗
20. Shen F. · Med. Gas Res. · 2019 · 9 · 8810.4103/2045-9912.260650 ↗
21. 10.1016/j.amjcard.2008.02.00310.1016/j.amjcard.2008.02.003 ↗
22. 10.1038/nature1390910.1038/nature13909 ↗
23. 10.1002/adma.20200490110.1002/adma.202004901 ↗
24. 10.1152/physrev.00018.200110.1152/physrev.00018.2001 ↗
25. 10.1093/toxsci/60.2.27110.1093/toxsci/60.2.271 ↗
26. 10.1002/biof.4810.1002/biof.48 ↗
27. 10.1016/j.addr.2009.01.00110.1016/j.addr.2009.01.001 ↗
28. 10.1007/s00253-013-4775-310.1007/s00253-013-4775-3 ↗
29. “International Report on organ donation and transplantation activities ”http://www.transplant-observatory.org/(accessed: 2021).
30. 10.1038/nnano.2012.26410.1038/nnano.2012.264 ↗
31. 10.1007/s12274-016-1128-410.1007/s12274-016-1128-4 ↗
32. 10.1002/adma.20170744310.1002/adma.201707443 ↗
33. 10.1034/j.1600-051x.2000.027012918.x10.1034/j.1600-051x.2000.027012918.x ↗
34. 10.1016/S0005-2736(02)00457-110.1016/S0005-2736(02)00457-1 ↗
35. 10.1016/j.jconrel.2017.11.04410.1016/j.jconrel.2017.11.044 ↗
36. 10.1021/nl401215n10.1021/nl401215n ↗
37. 10.1002/anie.20070112510.1002/anie.200701125 ↗
38. 10.1002/smll.20140155910.1002/smll.201401559 ↗
39. 10.1038/jcbfm.2012.20910.1038/jcbfm.2012.209 ↗
40. 10.1007/s12010-013-0427-410.1007/s12010-013-0427-4 ↗
41. 10.3390/pharmaceutics1202011510.3390/pharmaceutics12020115 ↗
42. 10.1007/s12274-017-1898-310.1007/s12274-017-1898-3 ↗
43. 10.1002/adma.20180755710.1002/adma.201807557 ↗
44. 10.1039/D0NR06823C10.1039/D0NR06823C ↗
45. 10.1038/7894810.1038/78948 ↗
46. 10.1021/acscatal.9b0241310.1021/acscatal.9b02413 ↗
47. 10.1016/S0022-1759(96)00244-X10.1016/S0022-1759(96)00244-X ↗
48. 10.1093/oxfordjournals.jbchem.a12751810.1093/oxfordjournals.jbchem.a127518 ↗
49. 10.1111/j.1432-1033.1971.tb01229.x10.1111/j.1432-1033.1971.tb01229.x ↗
50. 10.1016/j.ejpb.2018.05.03410.1016/j.ejpb.2018.05.034 ↗
51. 10.1063/1.300926310.1063/1.3009263 ↗
52. 10.2533/chimia.1997.3410.2533/chimia.1997.34 ↗
53. 10.1074/jbc.M111.26789810.1074/jbc.M111.267898 ↗
54. 10.1074/jbc.M70859720010.1074/jbc.M708597200 ↗
55. 10.4049/jimmunol.173.6.358910.4049/jimmunol.173.6.3589 ↗
56. 10.1021/acsnano.6b0208610.1021/acsnano.6b02086 ↗
57. 10.1038/nmat471810.1038/nmat4718 ↗
58. 10.1038/nbt.333010.1038/nbt.3330 ↗
59. 10.1021/mp800051m10.1021/mp800051m ↗
60. 10.1016/S0891-5849(02)01167-X10.1016/S0891-5849(02)01167-X ↗
61. 10.3748/wjg.v12.i38.621210.3748/wjg.v12.i38.6212 ↗
62. 10.5812/hepatmon.509010.5812/hepatmon.5090 ↗
63. 10.1023/A:102290912799210.1023/A:1022909127992 ↗
64. 10.1016/j.mrfmmm.2011.02.01510.1016/j.mrfmmm.2011.02.015 ↗
65. 10.2174/156720504333203610.2174/1567205043332036 ↗
66. 10.1016/j.reprotox.2009.04.00310.1016/j.reprotox.2009.04.003 ↗
67. 10.1006/scdb.2001.028210.1006/scdb.2001.0282 ↗
68. 10.1016/j.clon.2014.02.00310.1016/j.clon.2014.02.003 ↗