DataVXAdvanced MaterialsPaper
journal article·2023-08Open access

Metasurfaces‐Driven Hyperspectral Imaging via Multiplexed Plasmonic Resonance Energy Transfer

Inki Kim, Hongyoon Kim, Seungyeon Han, Joohoon Kim, Yangkyu Kim, Seonghyeon Eom, Aleksandr Barulin, Inhee Choi, Junsuk Rho, Luke P. Lee

Advanced Materials· Volume 35· Issue 32
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Source abstract

Abstract

Abstract Obtaining single–molecular–level fingerprints of biomolecules and electron–transfer dynamic imaging in living cells are critically demanded in postgenomic life sciences and medicine. However, the possible solution called plasmonic resonance energy transfer (PRET) spectroscopy remains challenging due to the fixed scattering spectrum of a plasmonic nanoparticle and limited multiplexing. Here, multiplexed metasurfaces‐driven PRET hyperspectral imaging, to probe biological light–matter interactions, is reported. Pixelated metasurfaces with engineered scattering spectra are first designed over the entire visible range by the precision nanoengineering of gap plasmon and grating effects of metasurface clusters. Pixelated metasurfaces are created and their full dark‐field coloration is optically characterized with visible color palettes and high‐resolution color printings of the art pieces. Furthermore, three different biomolecules (i.e., chlorophyll a, chlorophyll b, and cytochrome c) are applied on metasurfaces for color palettes to obtain selective molecular fingerprint imaging due to the unique biological light–matter interactions with application‐specific biomedical metasurfaces. This metasurface‐driven PRET hyperspectral imaging will open up a new path for multiplexed real‐time molecular sensing and imaging methods.
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Research context

Nanomaterials

OpenAlex topics: Gold and Silver Nanoparticles Synthesis and Applications · Advanced biosensing and bioanalysis techniques · Metamaterials and Metasurfaces Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biophysics Institute of Quantum Biophysics Sungkyunkwan University Suwon 16419 Republic of Korea

Department of Intelligent Precision Healthcare Convergence Sungkyunkwan University Suwon 16419 Republic of Korea

Department of Mechanical Engineering Pohang University of Science and Technology (POSTECH) Pohang 37673 Republic of Korea

Department of Life Science University of Seoul Seoul 02504 Republic of Korea

Department of Applied Chemistry University of Seoul Seoul 02504 Republic of Korea

Department of Chemical Engineering Pohang University of Science and Technology (POSTECH) Pohang 37673 Republic of Korea

POSCO‐POSTECH‐RIST Convergence Research Center for Flat Optics and Metaphotonics Pohang 37673 Republic of Korea

National Institute of Nanomaterials Technology (NINT) Pohang 37673 Republic of Korea

Department of Medicine Harvard Medical School Brigham and Women's Hospital Boston MA 02115 USA

Department of Bioengineering University of California at Berkeley Berkeley CA 94720 USA

Department of Electrical Engineering and Computer Science University of California at Berkeley Berkeley CA 94720 USA

Funding

Samsung · National Research Foundation of Korea · Pohang University of Science and Technology · Air Force Office of Scientific Research

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