DataVXAdvanced MaterialsPaper
journal article·2022-09

Edge‐Site Engineering of Defective Fe–N4 Nanozymes with Boosted Catalase‐Like Performance for Retinal Vasculopathies (Adv. Mater. 39/2022)

Ruofei Zhang, Bai Xue, Yanhong Tao, Hanqing Zhao, Zixia Zhang, Xiaonan Wang, Xinyao Zhou, Bing Jiang, Zhenglin Yang, Xiyun Yan, Kelong Fan

Advanced Materials· Volume 34· Issue 39
Publisher page
Source abstract

Abstract

High-Performance Nanozymes In article number 2205324, Zhenglin Yang, Xiyun Yan, Kelong Fan, and co-workers report a high-performance catalase-like iron single-atom nanozyme prepared by edge-site engineering. Hierarchical mesoporous and edge-hosted atomic sites are formed during the pyrolysis process, enabling efficient catalytic decomposition of H2O2 into O2 and H2O. Based on the catalase-like activity, effective treatment of retinal vasculopathies is realized by intravitreal administration of the nanozyme.
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Research context

NanomaterialsCatalysis & surfaces

OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanocluster Synthesis and Applications · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

CAS Engineering Laboratory for Nanozyme Key Laboratory of Protein and Peptide Pharmaceutical Institute of Biophysics Chinese Academy of Sciences Beijing 100101 China

Sichuan Provincial Key Laboratory for Human Disease Gene Study Sichuan Provincial People's Hospital School of Medicine University of Electronic Science and Technology of China Chengdu 610072 China

Nanozyme Medical Center School of Basic Medical Sciences Zhengzhou University Zhengzhou 450052 China

College of Chemistry and Chemical Engineering Jiangxi Normal University Nanchang 330022 China

University of Chinese Academy of Sciences Chinese Academy of Sciences Beijing 101408 China

School of Engineering and Applied Science University of Pennsylvania Philadelphia 19104 USA

Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026) Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital Chengdu 610072 China

References

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