A Biomolecular “Ship‐in‐a‐Bottle”: Continuous RNA Synthesis Within Hollow Polymer Hydrogel Assemblies
Source abstract
Abstract
The use of micrometer-sized, monodisperse polymer hydrogel capsules that act as both microreactors and drug carriers for de novo synthesized RNA is demonstrated (see figure). These capsules are expected to have broad impact as biophysical tools for the study of encapsulated RNA and as new biocompatible delivery vehicles for the cellular delivery of RNA therapeutics. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: RNA Interference and Gene Delivery · Advanced biosensing and bioanalysis techniques · Fuel Cells and Related Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (24)
Show source-provided references
1. 10.1002/anie.20070553810.1002/anie.200705538 ↗
2. 10.1016/j.sbi.2008.04.00410.1016/j.sbi.2008.04.004 ↗
3. 10.1016/j.cell.2009.02.00710.1016/j.cell.2009.02.007 ↗
4. 10.1038/nrd274210.1038/nrd2742 ↗
5. 10.1002/1439-7633(20020503)3:5<409::AID-CBIC409>3.0.CO;2-P10.1002/1439-7633(20020503)3:5<409::AID-CBIC409>3.0.CO;2-P ↗
6. 10.1038/nature0701810.1038/nature07018 ↗
7. 10.1098/rstb.2007.206610.1098/rstb.2007.2066 ↗
8. 10.1021/la010887s10.1021/la010887s ↗
9. 10.1073/pnas.050373310210.1073/pnas.0503733102 ↗
10. 10.1016/j.cis.2004.07.00610.1016/j.cis.2004.07.006 ↗
11. 10.1039/B600460C10.1039/B600460C ↗
12. 10.1002/anie.20030056810.1002/anie.200300568 ↗
13. 10.1016/j.cocis.2006.05.00110.1016/j.cocis.2006.05.001 ↗
14. 10.1002/adfm.20080038810.1002/adfm.200800388 ↗
15. 10.1021/ja052716610.1021/ja0527166 ↗
16. 10.1002/anie.20080476310.1002/anie.200804763 ↗
17. 10.1016/j.biomaterials.2009.05.07810.1016/j.biomaterials.2009.05.078 ↗
18. 10.1039/b610778h10.1039/b610778h ↗
19. 10.1021/nn700063w10.1021/nn700063w ↗
20. 10.1021/jp035821f10.1021/jp035821f ↗
21. See Experimental section and the Supporting Information for details.
22. 10.1002/adma.20080247510.1002/adma.200802475 ↗
23. 10.1002/adfm.20090129710.1002/adfm.200901297 ↗
24. 10.1002/adma.20080182610.1002/adma.200801826 ↗