DataVXAdvanced MaterialsPaper
journal article·2017-04

Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy

Quanyin Hu, Wujin Sun, Chenggen Qian, Hunter N. Bomba, Hongliang Xin, Zhen Gu

Advanced Materials· Volume 29· Issue 13
Publisher page
Source abstract

Abstract

A “relay drug delivery” system based on two distinct modules, which is composed of a signal transmission nanocarrier A (NCA) that can specifically induce tumor blood vessel inflammation generation and an execution biomimetic nanocarrier B (NCB) that can accumulate at the tumor site by receiving the broadcasting signals generated by NCA, is developed for amplifying active tumor targeting signal and enhancing antitumor therapy.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: RNA Interference and Gene Delivery · Advanced biosensing and bioanalysis techniques · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill and North Carolina State University Raleigh NC 27695 USA

Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery Eshelman School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA

Department of Polymer Science and Engineering and Key Laboratory of High Performance Polymer Materials and Technology of MOE School of Chemistry and Chemical Engineering Nanjing University Nanjing 210023 China

Department of Medicine University of North Carolina School of Medicine Chapel Hill NC 27599 USA

Funding

National Institutes of Health · Alfred P. Sloan Foundation

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