journal article·2023-12

MXene‐Based Functional Platforms for Tumor Therapy

Fan Gao, Chun Xue, Tian Zhang, Lu Zhang, Guo‐Yin Zhu, Changjin Ou, Yi‐Zhou Zhang, Xiaochen Dong

Advanced Materials· Volume 35· Issue 51
Publisher page

Abstract

Abstract Recently, 2D transition metal carbide, nitride, and carbonitrides (MXenes) materials stand out in the field of tumor therapy, particularly in the construction of functional platforms for optimal antitumor therapy due to their high specific surface area, tunable performance, strong absorption of near‐infrared light as well as preferable surface plasmon resonance effect. In this review, the progress of MXene‐mediated antitumor therapy is summarized after appropriate modifications or integration procedures. The enhanced antitumor treatments directly performed by MXenes, the significant improving effect of MXenes on different antitumor therapies, as well as the MXene‐mediated imaging‐guided antitumor strategies are discussed in detail. Moreover, the existing challenges and future development directions of MXenes in tumor therapy are presented.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: MXene and MAX Phase Materials · Graphene and Nanomaterials Applications · Advanced biosensing and bioanalysis techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute of Advanced Materials and Flexible Electronics (IAMFE) School of Chemistry and Materials Science Nanjing University of Information Science & Technology Nanjing 210044 China

Key Laboratory of Flexible Electronics (KLOFE) Institute of Advanced Materials (IAM) Nanjing Tech University (NanjingTech) Nanjing 211816 China

National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy the Second Affiliated Hospital of Xi'an Jiaotong University Xi'an 710004 China

School of Chemistry & Materials Science Jiangsu Normal University Xuzhou 221116 China

Funding

National Natural Science Foundation of China · Startup Foundation for Introducing Talent of Nanjing University of Information Science and Technology

References (100+)

Show source-provided references
1. 10.1111/cpr.1286510.1111/cpr.12865 ↗
2. 10.1002/ddr.2168310.1002/ddr.21683 ↗
3. 10.1016/j.biomaterials.2020.12047810.1016/j.biomaterials.2020.120478 ↗
4. 10.1016/j.biomaterials.2020.11979110.1016/j.biomaterials.2020.119791 ↗
5. 10.1016/j.ccr.2023.21502710.1016/j.ccr.2023.215027 ↗
6. 10.1038/s41417-020-00208-110.1038/s41417-020-00208-1 ↗
7. 10.1002/adtp.20220002710.1002/adtp.202200027 ↗
8. 10.1002/adfm.20191067610.1002/adfm.201910676 ↗
9. 10.1016/j.addr.2021.11390710.1016/j.addr.2021.113907 ↗
10. 10.1002/adma.20190240910.1002/adma.201902409 ↗
11. 10.1002/adma.20211030510.1002/adma.202110305 ↗
12. 10.1002/smtd.20220085310.1002/smtd.202200853 ↗
13. 10.1016/j.biomaterials.2020.12016710.1016/j.biomaterials.2020.120167 ↗
14. 10.1021/acsnano.9b0538310.1021/acsnano.9b05383 ↗
15. 10.1093/nsr/nwac04110.1093/nsr/nwac041 ↗
16. 10.1039/D0BM01875A10.1039/D0BM01875A ↗
17. 10.1016/j.biomaterials.2019.11949810.1016/j.biomaterials.2019.119498 ↗
18. 10.1002/smll.20220059510.1002/smll.202200595 ↗
19. 10.1002/adma.20190233310.1002/adma.201902333 ↗
20. 10.1002/advs.20210258710.1002/advs.202102587 ↗
21. 10.1002/adfm.20220343010.1002/adfm.202203430 ↗
22. 10.1002/adma.20210856010.1002/adma.202108560 ↗
23. 10.1002/adfm.20200071210.1002/adfm.202000712 ↗
24. 10.1002/anbr.20220006410.1002/anbr.202200064 ↗
25. 10.1002/anie.20201618110.1002/anie.202016181 ↗
26. 10.1007/s40820-022-00901-w10.1007/s40820-022-00901-w ↗
27. 10.1021/acs.nanolett.6b0433910.1021/acs.nanolett.6b04339 ↗
28. 10.1002/tcr.20220001910.1002/tcr.202200019 ↗
29. 10.1002/adfm.20210444010.1002/adfm.202104440 ↗
30. 10.1021/jacs.7b0781810.1021/jacs.7b07818 ↗
31. 10.1016/j.ccr.2022.21500210.1016/j.ccr.2022.215002 ↗
32. 10.1016/j.jmbbm.2012.11.01410.1016/j.jmbbm.2012.11.014 ↗
33. 10.3390/nano1109244910.3390/nano11092449 ↗
34. 10.1002/adfm.20190950410.1002/adfm.201909504 ↗
35. 10.1002/chem.20170419710.1002/chem.201704197 ↗
36. 10.1016/j.nantod.2019.02.01210.1016/j.nantod.2019.02.012 ↗
37. 10.1186/s12951-023-01809-210.1186/s12951-023-01809-2 ↗
38. 10.3390/mi1310177310.3390/mi13101773 ↗
39. 10.1002/smll.20180473610.1002/smll.201804736 ↗
40. 10.3390/pharmaceutics1402030410.3390/pharmaceutics14020304 ↗
41. 10.1039/C9NR07616F10.1039/C9NR07616F ↗
42. 10.1016/j.jconrel.2020.06.03210.1016/j.jconrel.2020.06.032 ↗
43. 10.2147/IJN.S23975110.2147/IJN.S239751 ↗
44. 10.1002/anie.20191147710.1002/anie.201911477 ↗
45. 10.1002/adom.20200065210.1002/adom.202000652 ↗
46. 10.1021/acs.jpcc.5b0353110.1021/acs.jpcc.5b03531 ↗
47. 10.1021/acsbiomaterials.0c0176310.1021/acsbiomaterials.0c01763 ↗
48. 10.1002/adfm.20190194210.1002/adfm.201901942 ↗
49. 10.1002/adma.20170328410.1002/adma.201703284 ↗
50. 10.1002/smll.20190681410.1002/smll.201906814 ↗
51. 10.7150/thno.2799510.7150/thno.27995 ↗
52. 10.1021/acsami.7b1342110.1021/acsami.7b13421 ↗
53. 10.1039/C7NR05997C10.1039/C7NR05997C ↗
54. 10.1002/smll.20220064610.1002/smll.202200646 ↗
55. 10.1016/j.ccr.2021.21408710.1016/j.ccr.2021.214087 ↗
56. 10.1039/D2RA03786F10.1039/D2RA03786F ↗
57. 10.1039/D0MH00613K10.1039/D0MH00613K ↗
58. 10.1016/j.nantod.2022.10143410.1016/j.nantod.2022.101434 ↗
59. 10.1021/acsnano.3c0004110.1021/acsnano.3c00041 ↗
60. 10.1002/anie.20200489410.1002/anie.202004894 ↗
61. 10.1007/s12274-020-2992-510.1007/s12274-020-2992-5 ↗
62. 10.1016/j.bioactmat.2021.06.02110.1016/j.bioactmat.2021.06.021 ↗
63. 10.1016/j.nantod.2022.10175010.1016/j.nantod.2022.101750 ↗
64. 10.1016/j.carbon.2021.04.07010.1016/j.carbon.2021.04.070 ↗
65. 10.1039/D1SC07073H10.1039/D1SC07073H ↗
66. 10.1016/j.nantod.2021.10127310.1016/j.nantod.2021.101273 ↗
67. 10.1016/j.ultsonch.2011.09.00910.1016/j.ultsonch.2011.09.009 ↗
68. 10.1038/srep2320010.1038/srep23200 ↗
69. 10.1021/acsnano.2c0463010.1021/acsnano.2c04630 ↗
70. 10.1002/smll.20210386810.1002/smll.202103868 ↗
71. 10.1002/adhm.20210197110.1002/adhm.202101971 ↗
72. 10.1002/adfm.20200030810.1002/adfm.202000308 ↗
73. 10.1016/j.colsurfb.2022.11300510.1016/j.colsurfb.2022.113005 ↗
74. 10.1002/smll.20210170510.1002/smll.202101705 ↗
75. 10.1515/nanoph-2022-053310.1515/nanoph-2022-0533 ↗
76. 10.1016/j.pdpdt.2018.03.00610.1016/j.pdpdt.2018.03.006 ↗
77. 10.1002/VIW.2020014710.1002/VIW.20200147 ↗
78. 10.2147/IJN.S30788510.2147/IJN.S307885 ↗
79. 10.3389/fphar.2018.0139410.3389/fphar.2018.01394 ↗
80. 10.1021/acs.nanolett.8b0317810.1021/acs.nanolett.8b03178 ↗
81. 10.1007/s12274-022-4165-110.1007/s12274-022-4165-1 ↗
82. 10.1021/acsami.9b0825710.1021/acsami.9b08257 ↗
83. 10.1021/acsami.9b1359810.1021/acsami.9b13598 ↗
84. Wang Z. · Anal. Chem. · 2023 · 95 · 1710
85. 10.1002/EXP.2021000510.1002/EXP.20210005 ↗
86. 10.1002/adma.20200224610.1002/adma.202002246 ↗
87. 10.1002/adma.20210708810.1002/adma.202107088 ↗
88. 10.1039/C7CS00471K10.1039/C7CS00471K ↗
89. 10.1002/adma.20210055610.1002/adma.202100556 ↗
90. 10.1002/adma.20200243910.1002/adma.202002439 ↗
91. 10.1021/acsnano.1c1073210.1021/acsnano.1c10732 ↗
92. 10.1039/D1RA05407D10.1039/D1RA05407D ↗
93. 10.1016/j.cej.2022.13784710.1016/j.cej.2022.137847 ↗
94. 10.1002/adma.20180536810.1002/adma.201805368 ↗
95. 10.1039/C8CS00718G10.1039/C8CS00718G ↗
96. 10.1016/j.cej.2021.13063910.1016/j.cej.2021.130639 ↗
97. 10.1002/adhm.20220215410.1002/adhm.202202154 ↗
98. 10.1016/j.pdpdt.2019.04.03310.1016/j.pdpdt.2019.04.033 ↗
99. 10.1021/cr500419810.1021/cr5004198 ↗
100. 10.1002/cam4.359210.1002/cam4.3592 ↗