journal article·2021-07

Functional Micro‐/Nanomaterials for Multiplexed Biodetection

Xinyi Liu, Weijie Wu, Daxiang Cui, Xiaoyuan Chen, Wanwan Li

Advanced Materials· Volume 33· Issue 30
Publisher page

Abstract

Abstract When analyzing biological phenomena and processes, multiplexed biodetection has many advantages over single‐factor biodetection and is highly relevant to both human health issues and advancements in the life sciences. However, many key problems with current multiplexed biodetection strategies remain unresolved. Herein, the main issues are analyzed and summarized: 1) generating sufficient signal to label targets, 2) improving the signal‐to‐noise ratio to ensure total detection sensitivity, and 3) simplifying the detection process to reduce the time and labor costs of multiple target detection. Then, available solutions made possible by designing and controlling the properties of micro‐ and nanomaterials are introduced. The aim is to emphasize the role that micro‐/nanomaterials can play in the improvement of multiplexed biodetection strategies. Through analyzing existing problems, introducing state‐of‐the‐art developments regarding relevant materials, and discussing future directions of the field, it is hopeful to help promote necessary developments in multiplexed biodetection and associated scientific research.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Biosensors and Analytical Detection · Advanced Biosensing Techniques and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Lab of Metal Matrix Composites School of Materials Science and Engineering Key Laboratory of Systems Biomedicine (Ministry of Education) Shanghai Center for Systems Biomedicine Shanghai Jiao Tong University 800 Dongchuan Road Shanghai 200240 P. R. China

Department of Instrument Science and Engineering School of Electronic Information and Electrical Engineering Shanghai Engineering Research Center for Intelligent Diagnosis and Treatment Instrument Key Laboratory of Thin Film and Microfabrication (Ministry of Education) Shanghai Jiao Tong University 800 Dongchuan Road Shanghai 200240 P. R. China

Yong Loo Lin School of Medicine and Faculty of Engineering National University of Singapore Singapore 117597 Singapore

Funding

National Natural Science Foundation of China · National Basic Research Program of China

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