journal article·2022-03

A Biocompatible Vibration‐Actuated Omni‐Droplets Rectifier with Large Volume Range Fabricated by Femtosecond Laser

Yiyuan Zhang, Jing Li, Le Xiang, Jinxing Wang, Tao Wu, Yunlong Jiao, Shaojun Jiang, Chuanzong Li, Shengying Fan, Juan Zhang, Hao Wu, Yuxuan Zhang, Yucheng Bian, Kun Zhao, Yubin Peng, Wulin Zhu, Jiawen Li, Yanlei Hu, Dong Wu, Jiaru Chu, Zuankai Wang

Advanced Materials· Volume 34· Issue 12
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Abstract

Abstract High‐performance droplet transport is crucial for diverse applications including biomedical detection, chemical micro‐reaction, and droplet microfluidics. Despite extensive progress, traditional passive and active strategies are restricted to limited liquid types, small droplet volume ranges, and poor biocompatibilities. Moreover, more challenges occur for biological fluids due to large viscosity and low surface tension. Here, a vibration‐actuated omni‐droplets rectifier (VAODR) consisting of slippery ratchet arrays fabricated by femtosecond laser and vibration platforms is reported. Through the relative competition between the asymmetric adhesive resistance originating from the lubricant meniscus on the VAODR and the periodic inertial driving force originating from isotropic vibration, the fast (up to ≈60 mm s−1), programmable, and robust transport of droplets is achieved for a large volume range (0.05–2000 µL, Vmax/Vmin ≈ 40 000) and in various transport modes including transport of liquid slugs in tubes, programmable and sequential transport, and bidirectional transport. This VAODR is general to a high diversity of biological and medical fluids, and thus can be used for biomedical detection including ABO blood‐group tests and anticancer drugs screening. These strategies provide a complementary and promising platform for maneuvering omni‐droplets that are fundamental to biomedical applications and other high‐throughput omni‐droplet operation fields.
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Research context

OpenAlex topics: Surface Modification and Superhydrophobicity · Innovative Microfluidic and Catalytic Techniques Innovation · Electrowetting and Microfluidic Technologies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

CAS Key Laboratory of Mechanical Behavior and Design of Materials Key Laboratory of Precision Scientific Instrumentation of Anhui Higher Education Institutes Department of Precision Machinery and Precision Instrumentation University of Science and Technology of China Hefei 230027 China

Department of Mechanical Engineering City University of Hong Kong Hong Kong China

School of Instrument Science and Opto‐electronics Engineering Hefei University of Technology Hefei 230009 P. R. China

Department of Modern Mechanics University of Science and Technology of China Hefei 230027 China

Institute of Tribology Hefei University of Technology Hefei 230009 P. R. China

Center for Biomedical Engineering Department of Electronic Science and Technology University of Science and Technology of China Hefei 230026 China

Department of Clinical Laboratory The First Affiliated Hospital of USTC Division of Life Sciences and Medicine University of Science and Technology of China Hefei Anhui 230001 China

Information Materials and Intelligent Sensing Laboratory of Anhui Province School of Electronics and Information Engineering Anhui University Hefei 230039 China

Funding

National Natural Science Foundation of China · Fundamental Research Funds for the Central Universities

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