DataVXAdvanced MaterialsPaper
journal article·2020-09

DNA Micro‐Disks for the Management of DNA‐Based Data Storage with Index and Write‐Once–Read‐Many (WORM) Memory Features

Yeongjae Choi, Hyung Jong Bae, Amos C. Lee, Hansol Choi, Daewon Lee, Taehoon Ryu, Jinwoo Hyun, Seojoo Kim, Hyeli Kim, Suk‐Heung Song, Kibeom Kim, Wook Park, Sunghoon Kwon

Advanced Materials· Volume 32· Issue 37
Publisher page
Source abstract

Abstract

Abstract DNA‐based data storage has attracted attention because of its higher physical density of the data and longer retention time than those of conventional digital data storage. However, previous DNA‐based data storage lacked index features and the data quality of storage after a single access was not preserved, obstructing its industrial use. Here, DNA micro‐disks, QR‐coded micro‐sized disks that harbor data‐encoded DNA molecules for the efficient management of DNA‐based data storage, are proposed. The two major features that previous DNA‐based data‐storage studies could not achieve are demonstrated. One feature is accessing data items efficiently by indexing the data‐encoded DNA library. Another is achieving write‐once–read‐many (WORM) memory through the immobilization of DNA molecules on the disk and their enrichment through in situ DNA production. Through these features, the reliability of DNA‐based data storage is increased by allowing selective and multiple accession of data‐encoded DNA with lower data loss than previous DNA‐based data storage methods.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: DNA and Biological Computing · Advanced biosensing and bioanalysis techniques · Modular Robots and Swarm Intelligence

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Nano Systems Institute Seoul National University 1, Gwanak‐ro, Gwanak‐gu Seoul 08826 Republic of Korea

Department of Electrical and Computer Engineering Seoul National University 1, Gwanak‐ro, Gwanak‐gu Seoul 08826 Republic of Korea

Interdisciplinary Program for Bioengineering Seoul National University 1, Gwanak‐ro, Gwanak‐gu Seoul 08826 Republic of Korea

BK21+ Creative Research Engineer Development for IT Seoul National University 1, Gwanak‐ro, Gwanak‐gu Seoul 08826 Republic of Korea

Celemics Inc., 131 Gasandigital 1‐ro, Geumcheon‐gu Seoul 08506 Republic of Korea

Department of Electronic Engineering Kyung Hee University Deogyeong‐daero, Giheung‐gu Yongin‐si Gyeonggi‐do 17104 Republic of Korea

Institute for Wearable Convergence Electronics Kyung Hee University Deogyeong‐daero, Giheung‐gu Yongin‐si Gyeonggi‐do 17104 Republic of Korea

Institute of Entrepreneurial Bio Convergence Seoul National University 1, Gwanak‐ro, Gwanak‐gu Seoul 08826 Republic of Korea

Seoul National University Hospital Biomedical Research Institute Seoul National University Hospital 101, Daehak‐ro, Jongno‐gu Seoul 03080 Republic of Korea

Funding

National Research Foundation of Korea · National Science Foundation, United Arab Emirates · Ministry of Education · Kyung Hee University

References (29)

Show source-provided references
1. 10.1038/s41467-019-10258-110.1038/s41467-019-10258-1 ↗
2. 10.1126/science.122635510.1126/science.1226355 ↗
3. 10.1038/srep3717610.1038/srep37176 ↗
4. 10.1126/science.aaj203810.1126/science.aaj2038 ↗
5. 10.1038/nbt.407910.1038/nbt.4079 ↗
6. 10.1038/s41598-019-43105-w10.1038/s41598-019-43105-w ↗
7. 10.1587/transfun.E100.A.240810.1587/transfun.E100.A.2408 ↗
8. 10.1038/537022a10.1038/537022a ↗
9. 10.1038/nmat459410.1038/nmat4594 ↗
10. 10.1002/anie.20141137810.1002/anie.201411378 ↗
11. 10.1002/0471142727.mb0721s11210.1002/0471142727.mb0721s112 ↗
12. 10.1186/gb-2011-12-2-r1810.1186/gb-2011-12-2-r18 ↗
13. 10.1093/nar/gku130310.1093/nar/gku1303 ↗
14. Miller L. C. · 2013
15. D.Pease A.Amir L.Villa Real B.Biskeborn M.Richmond A.Abek in2010 IEEE 26th Symp. Mass Storage Syst. Technol. MSST2010 IEEE Piscataway NJ USA2010 https://doi.org/10.1109/MSST.2010.5496989.10.1109/MSST.2010.5496989 ↗
16. 10.1038/s41467-019-09517-y10.1038/s41467-019-09517-y ↗
17. 10.1038/ncomms797610.1038/ncomms7976 ↗
18. 10.1002/smll.20150296810.1002/smll.201502968 ↗
19. 10.1002/advs.20180138010.1002/advs.201801380 ↗
20. 10.1002/adma.20150330810.1002/adma.201503308 ↗
21. 10.1002/adma.20120148610.1002/adma.201201486 ↗
22. 10.1063/1.496737310.1063/1.4967373 ↗
23. 10.1063/1.503059710.1063/1.5030597 ↗
24. Organick L. · bioRxiv. · 2019
25. 10.1109/JPROC.2018.287538610.1109/JPROC.2018.2875386 ↗
26. Brandt S. A. · 2003 · 290
27. 10.1371/journal.pcbi.100509710.1371/journal.pcbi.1005097 ↗
28. 10.1021/ac061358210.1021/ac0613582 ↗
29. 10.1002/smll.20190260710.1002/smll.201902607 ↗