journal article·2013-01-25Open access

Fragmentation of Poly(lactic acid) Nanosheets and Patchwork Treatment for Burn Wounds

Yosuke Okamura, Koki Kabata, Manabu Kinoshita, Hiromi Miyazaki, Akihiro Saito, Toshinori Fujie, Shinya Ohtsubo, Daizoh Saitoh, Shinji Takeoka

Advanced Materials· Volume 25· Issue 4

Abstract

Freestanding poly(L-lactic acid) (PLLA) nanosheets are mass-produced by a simple combination of a spin-coating-assisted multi-layering process and a peeling technique. The resulting PLLA nanosheets are fragmented by homogenization and then reconstructed into a "patchwork" sheet on various surfaces without any adhesive reagents. The patchwork is shown to offer excellent protection against burn wound infection with Pseudomonas aeruginosa, and may therefore be an alternative to conventional burn therapy for prevention of infection.
Source: europepmc · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Polymer Surface Interaction Studies · biodegradable polymer synthesis and properties · Bone Tissue Engineering Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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