journal article·2009-07-20Open access

Mapping the Interactions among Biomaterials, Adsorbed Proteins, and Human Embryonic Stem Cells

Ying Mei, Sharon Gerecht, Michael Taylor, Andrew J. Urquhart, Said R. Bogatyrev, Seung‐Woo Cho, Martyn C. Davies, Morgan R. Alexander, Robert S. Langer, Daniel G. Anderson

Advanced Materials· Volume 21· Issue 27

Abstract

An integrated high-throughput polymer synthesis and rapid material/protein/cell interaction assays were developed to optimize stem cell microenvironments. Microarrayed polymers were synthesized and studied for the ability to support the growth of partially differentiated human embryonic stem cells. In parallel, a programmed laser scanning cytometry system was developed to allow for rapid quantification of cell material interaction. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Research context

OpenAlex topics: 3D Printing in Biomedical Research · Cellular Mechanics and Interactions · Microfluidic and Bio-sensing Technologies

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