journal article·2016-03Open access

Rapid Reversible Photoswitching of Integrin‐Mediated Adhesion at the Single‐Cell Level

Laith F. Kadem, Michelle Holz, Kristine Grace Suana, Qian Li, Constanze Lamprecht, Rainer Herges, Christine Selhuber‐Unkel

Advanced Materials· Volume 28· Issue 9

Abstract

Rapid and reversible photoswitching of cell adhesion is achieved by c(RGDfK)-azobenzenes embedded in a poly(ethylene glycol) background on surfaces. The light-induced cis-trans-isomerization of the azobenzene enables switching of cell adhesion on the surface. Reversibility of switching over several consecutive switching cycles is demonstrated by single-cell force spectroscopy.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Photochromic and Fluorescence Chemistry · Cell Adhesion Molecules Research · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute for Materials Science University of Kiel Kaiserstr. 2 24143 Kiel Germany

Otto‐Diels‐Institute of Organic Chemistry University of Kiel Otto‐Hahn‐Platz 4 24098 Kiel Germany

Funding

Deutsche Forschungsgemeinschaft · European Research Council · Marie Curie Actions Intra European Fellowship

References (30)

Show source-provided references
1. 10.1152/physrev.00002.200410.1152/physrev.00002.2004 ↗
2. 10.1101/cshperspect.a00503310.1101/cshperspect.a005033 ↗
3. 10.1016/j.devcel.2013.02.01210.1016/j.devcel.2013.02.012 ↗
4. 10.1242/jcs.06618310.1242/jcs.066183 ↗
5. 10.1002/adma.20110092510.1002/adma.201100925 ↗
6. 10.1016/j.biomaterials.2011.12.01210.1016/j.biomaterials.2011.12.012 ↗
7. 10.1021/ja038265b10.1021/ja038265b ↗
8. 10.1016/j.actbio.2013.06.01910.1016/j.actbio.2013.06.019 ↗
9. 10.1038/nmat415710.1038/nmat4157 ↗
10. 10.1016/j.biomaterials.2008.01.00410.1016/j.biomaterials.2008.01.004 ↗
11. 10.1016/j.biomaterials.2008.12.02610.1016/j.biomaterials.2008.12.026 ↗
12. 10.1002/adma.20090410210.1002/adma.200904102 ↗
13. 10.1242/jcs.0309810.1242/jcs.03098 ↗
14. 10.1021/ja053648q10.1021/ja053648q ↗
15. 10.1002/anie.20090113010.1002/anie.200901130 ↗
16. 10.1021/bm301037k10.1021/bm301037k ↗
17. 10.1016/0278-6915(86)90187-010.1016/0278-6915(86)90187-0 ↗
18. 10.1007/s10856-010-4181-710.1007/s10856-010-4181-7 ↗
19. 10.1016/j.biomaterials.2007.11.00210.1016/j.biomaterials.2007.11.002 ↗
20. 10.1002/1439-7633(20000818)1:2<107::AID-CBIC107>3.0.CO;2-410.1002/1439-7633(20000818)1:2<107::AID-CBIC107>3.0.CO;2-4 ↗
21. 10.1021/la500766t10.1021/la500766t ↗
22. 10.1007/978-1-61779-105-5_2110.1007/978-1-61779-105-5_21 ↗
23. 10.1021/nl801483w10.1021/nl801483w ↗
24. 10.1083/jcb.20010710710.1083/jcb.200107107 ↗
25. 10.1039/B906608J10.1039/B906608J ↗
26. 10.1002/anie.19971374110.1002/anie.199713741 ↗
27. 10.1021/jp051785410.1021/jp0517854 ↗
28. 10.1021/la960433910.1021/la9604339 ↗
29. 10.1529/biophysj.108.13958410.1529/biophysj.108.139584 ↗
30. Franz C. M. · Sci. Signal. · 2007 · 2007 · pl5