journal article·2016-09

Controllable Self‐Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting

Hui Li, Kaiming Zhang, Fengmei Pi, Sijin Guo, Luda Shlyakhtenko, Wah Chiu, Dan Shu, Peixuan Guo

Advanced Materials· Volume 28· Issue 34
Publisher page

Abstract

RNA tetrahedral nanoparticles with two different sizes are successfully assembled by a one-pot bottom-up approach with high efficiency and thermal stability. The reported design principles can be extended to construct higher-order polyhedral RNA architectures for various applications such as targeted cancer imaging and therapy. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · RNA and protein synthesis mechanisms · RNA Interference and Gene Delivery

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

College of Pharmacy/Division of Pharmaceutics and Pharmaceutical Chemistry College of Medicine/Department of Physiology and Cell Biology/Dorothy M. Davis Heart and Lung Research Institute The Ohio State University Columbus OH 43210 USA

Verna and Marrs McLean Department of Biochemistry and Molecular Biology National Center for Macromolecular Imaging Baylor College of Medicine Houston TX 77030 USA

Department of Pharmaceutical Sciences University of Nebraska Medical Center Omaha NE 68198 USA

Funding

National Institutes of Health · U.S. Department of Defense

References (46)

Show source-provided references
1. 10.1038/nnano.2010.23110.1038/nnano.2010.231 ↗
2. 10.1016/j.nantod.2015.09.00310.1016/j.nantod.2015.09.003 ↗
3. 10.1016/j.addr.2013.11.00610.1016/j.addr.2013.11.006 ↗
4. 10.1146/annurev-biochem-060308-10224410.1146/annurev-biochem-060308-102244 ↗
5. 10.1021/ja505101a10.1021/ja505101a ↗
6. 10.1126/science.126090110.1126/science.1260901 ↗
7. 10.1021/nn500625410.1021/nn5006254 ↗
8. 10.1021/nn502160s10.1021/nn502160s ↗
9. 10.1021/nl900261h10.1021/nl900261h ↗
10. 10.1073/pnas.101799910810.1073/pnas.1017999108 ↗
11. 10.1021/nl049449710.1021/nl0494497 ↗
12. 10.1093/nar/gkl00810.1093/nar/gkl008 ↗
13. 10.1126/science.110468610.1126/science.1104686 ↗
14. 10.1016/S1097-2765(00)80124-010.1016/S1097-2765(00)80124-0 ↗
15. 10.1261/rna.037077.11210.1261/rna.037077.112 ↗
16. 10.1021/nl104271s10.1021/nl104271s ↗
17. 10.1038/ncomms489010.1038/ncomms4890 ↗
18. 10.1038/nchem.73310.1038/nchem.733 ↗
19. 10.1021/nl502385k10.1021/nl502385k ↗
20. 10.1126/science.310712410.1126/science.3107124 ↗
21. 10.1261/rna.037002.11210.1261/rna.037002.112 ↗
22. 10.1038/nprot.2013.09710.1038/nprot.2013.097 ↗
23. 10.1038/nnano.2011.10510.1038/nnano.2011.105 ↗
24. 10.1016/j.nantod.2012.06.01010.1016/j.nantod.2012.06.010 ↗
25. 10.1093/nar/gku51610.1093/nar/gku516 ↗
26. 10.1021/ja903768f10.1021/ja903768f ↗
27. 10.1021/nn403822310.1021/nn4038223 ↗
28. 10.1038/nnano.2012.7310.1038/nnano.2012.73 ↗
29. 10.1126/science.125094410.1126/science.1250944 ↗
30. 10.1021/bi401702210.1021/bi4017022 ↗
31. 10.1021/bi00035a02910.1021/bi00035a029 ↗
32. 10.1016/S0959-440X(03)00076-910.1016/S0959-440X(03)00076-9 ↗
33. 10.1261/rna.047506.11410.1261/rna.047506.114 ↗
34. 10.1002/jcc.2008410.1002/jcc.20084 ↗
35. Grodzinski P. · 2014
36. 10.1038/sj.gt.330200210.1038/sj.gt.3302002 ↗
37. 10.1006/jmbi.2000.395110.1006/jmbi.2000.3951 ↗
38. 10.1002/cbic.20030070110.1002/cbic.200300701 ↗
39. 10.1126/science.121829810.1126/science.1218298 ↗
40. 10.1017/S135583820100245X10.1017/S135583820100245X ↗
41. 10.1038/nrc160910.1038/nrc1609 ↗
42. 10.1371/journal.pone.002407110.1371/journal.pone.0024071 ↗
43. 10.1093/nar/gks29410.1093/nar/gks294 ↗
44. 10.1089/nat.2011.028310.1089/nat.2011.0283 ↗
45. 10.1073/pnas.133266010010.1073/pnas.1332660100 ↗
46. 10.1021/acsnano.5b0247110.1021/acsnano.5b02471 ↗