Generation of Novel Hybrid Aptamer–Molecularly Imprinted Polymeric Nanoparticles
Source abstract
Abstract
A strategy to exploit aptamers as recognition elements of molecularly imprinted polymeric nanoparticles (AptaMIP NPs) is presented, via modification of the chemical structure of the DNA. It is demonstrated that the introduction of this modified "aptamer monomer" results in an increase of the affinity of the produced MIP NPs, without altering their physical properties such as size, shape, or dispersibility.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Analytical chemistry methods development · Advanced biosensing and bioanalysis techniques · Polymer Surface Interaction Studies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Life, Health and Chemical Sciences The Open University Milton Keynes MK7 6AA UK
Department of Chemistry University of Southampton Highfield Southampton SO17 1BJ UK
Funding
Open University and of Engineering and Physical Sciences Research Council
References (68)
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