Independent Control of Topography for 3D Patterning of the ECM Microenvironment
Source abstract
Abstract
Biomimetic extracellular matrix (ECM) topographies driven by the magnetic-field-directed self-assembly of ECM protein-coated magnetic beads are fabricated. This novel bottom-up method allows us to program isotropic, anisotropic, and diverse hybrid ECM patterns without changing other physicochemical properties of the scaffold material. It is demonstrated that this 3D anisotropic matrix is able to guide the dendritic protrusion of cells.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Cellular Mechanics and Interactions · 3D Printing in Biomedical Research · Cell Adhesion Molecules Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Laboratory of Cell Biology Center for Cancer Research National Cancer Institute (NIH) Bethesda MD 20852 USA
Funding
Ministry of Health & Welfare, Republic of Korea
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