journal article·2017-03Open access

Amplified Photodegradation of Cell‐Laden Hydrogels via an Addition–Fragmentation Chain Transfer Reaction

Tobin E. Brown, Ian A. Marozas, Kristi S. Anseth

Advanced Materials· Volume 29· Issue 11

Abstract

Hydrogels crosslinked by allyl-sulfide-containing molecules are presented. By exposure to light in the presence of a photoinitiator and a free monofunctional thiol, photodegradation is achieved. Both the gelation and degradation are cytocompatible and allow for cell encapsulation and subsequent release. The photodegradation kinetics and depths attainable are superior to those of traditional cell-laden photodegradable hydrogels.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: 3D Printing in Biomedical Research · Hydrogels: synthesis, properties, applications · Photochromic and Fluorescence Chemistry

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Chemical and Biological Engineering and the BioFrontiers Institute University of Colorado Boulder Jennie Smoly Caruthers Biotechnology Building 3415 Colorado Ave Boulder CO 80303 USA

Howard Hughes Medical Institute University of Colorado Boulder Jennie Smoly Caruthers Biotechnology Building 3415 Colorado Ave Boulder CO 80303 USA

Funding

National Science Foundation · Howard Hughes Medical Institute · National Institutes of Health

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