Acetal‐Modified Dextran Microparticles with Controlled Degradation Kinetics and Surface Functionality for Gene Delivery in Phagocytic and Non‐Phagocytic Cells
Source abstract
Abstract
A microparticulate gene delivery system based on biodegradable and acid-sensitive acetal-modified dextran with unprecedented tunability of degradation rates and simplicity of surface functionalization is presented. When optimally formulated with small amounts of cationic polymers, these microparticles are capable of efficiently transfecting both phagocytic and non-phagocytic cells with minimal toxicity.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: RNA Interference and Gene Delivery · Virus-based gene therapy research · Membrane Separation Technologies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (30)
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