Spatially Gradated Hydrogel Platform as a 3D Engineered Tumor Microenvironment
Source abstract
Abstract
There is an acute need for biomaterial tools that recreate the heterogeneous brain-tumor microenvironment. A microfluidic mixing tool is reported to encapsulate glioblastoma multiforme cells within miniaturized gelatin hydrogels containing overlapping patterns of tumor-inspired matrix signals. This approach permits in situ analysis of glioma cells at the molecular and genomic level as well as the potential for clinical insight.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: 3D Printing in Biomedical Research · Innovative Microfluidic and Catalytic Techniques Innovation · Cancer Cells and Metastasis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
The Institute for Genomic Biology University of Illinois at Urbana‐Champaign 1206 West Gregory Drive Urbana Illinois 61801 USA
Department of Chemical and Biomolecular Engineering The Institute for Genomic Biology University of Illinois at Urbana‐Champaign, 110 Roger Adams Lab. 600 S. Mathews Avenue Urbana Illinois 61801 USA
Funding
National Science Foundation · Illini · Department of Chemical & Biomolecular Engineering · Institute for Genomic Biology at the University of Illinois at Urbana-Champaign
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