journal article·2008-05-19

Biodegradable Xylitol‐Based Polymers

Joost P. Bruggeman, Christopher J. Bettinger, Christiaan L.E. Nijst, Daniel S. Kohane, Robert Langer

Advanced Materials· Volume 20· Issue 10
Publisher page

Abstract

Synthetic polymers composed of metabolites endogenous to the mammalian organism are designed. The design is based on the monomer xylitol, which possesses a wide range of physical properties that are biologically relevant. Xylitol-based hydrogels and elastomers are biocompatible in vitro and in vivo, compared to the prevalent synthetic polymer poly(L-lactic-co- glycolic acid) (PLGA). It furthermore provides a platform to tune mechanical properties, degradation profiles, and cell attachment.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Hydrogels: synthesis, properties, applications · biodegradable polymer synthesis and properties · 3D Printing in Biomedical Research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (26)

Show source-provided references
1. 10.1126/science.849352910.1126/science.8493529 ↗
2. 10.1038/nbt0602-60210.1038/nbt0602-602 ↗
3. 10.1002/adma.20030626410.1002/adma.200306264 ↗
4. 10.1021/bm049508a10.1021/bm049508a ↗
5. 10.1002/1097-4636(200101)54:1<115::AID-JBM14>3.0.CO;2-Q10.1002/1097-4636(200101)54:1<115::AID-JBM14>3.0.CO;2-Q ↗
6. 10.1002/(SICI)1097-4636(199802)39:2<266::AID-JBM14>3.0.CO;2-B10.1002/(SICI)1097-4636(199802)39:2<266::AID-JBM14>3.0.CO;2-B ↗
7. 10.1111/j.1399-6576.1985.tb02336.x10.1111/j.1399-6576.1985.tb02336.x ↗
8. Talke H. · Infusionstherapie · 1973 · 1 · 49
9. 10.1016/S0922-338X(98)80026-310.1016/S0922-338X(98)80026-3 ↗
10. 10.1093/ajcn/65.4.94710.1093/ajcn/65.4.947 ↗
11. 10.1159/00009565010.1159/000095650 ↗
12. 10.1136/bmj.313.7066.118010.1136/bmj.313.7066.1180 ↗
13. 10.1016/S0264-410X(00)00294-210.1016/S0264-410X(00)00294-2 ↗
14. 10.1016/j.jcf.2006.05.00210.1016/j.jcf.2006.05.002 ↗
15. 10.1073/pnas.97.21.1161410.1073/pnas.97.21.11614 ↗
16. 10.1021/bm050213m10.1021/bm050213m ↗
17. 10.1021/ma049634710.1021/ma0496347 ↗
18. Ellingsworth L. R. · J. Immunol. · 1986 · 136 · 87710.4049/jimmunol.136.3.877 ↗
19. 10.1046/j.1524-4725.2000.99202.x10.1046/j.1524-4725.2000.99202.x ↗
20. 10.1016/S0022-4804(03)00255-510.1016/S0022-4804(03)00255-5 ↗
21. 10.1089/10763270332206664210.1089/107632703322066642 ↗
22. 10.1016/0021-9290(95)00152-210.1016/0021-9290(95)00152-2 ↗
23. 10.1007/s00586-007-0458-z10.1007/s00586-007-0458-z ↗
24. 10.1021/bm070423u10.1021/bm070423u ↗
25. Flory P. J. · 1953
26. 10.1002/adma.20050161210.1002/adma.200501612 ↗