journal article·2019-06Open access

3D Scaffolds to Study Basic Cell Biology

Marc Hippler, Enrico Domenico Lemma, Sarah Bertels, Eva Blasco, Christopher Barner‐Kowollik, Martin Wegener, Martin Bastmeyer

Advanced Materials· Volume 31· Issue 26

Abstract

Abstract Mimicking the properties of the extracellular matrix is crucial for developing in vitro models of the physiological microenvironment of living cells. Among other techniques, 3D direct laser writing (DLW) has emerged as a promising technology for realizing tailored 3D scaffolds for cell biology studies. Here, results based on DLW addressing basic biological issues, e.g., cell‐force measurements and selective 3D cell spreading on functionalized structures are reviewed. Continuous future progress in DLW materials engineering and innovative approaches for scaffold fabrication will enable further applications of DLW in applied biomedical research and tissue engineering.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: 3D Printing in Biomedical Research · Additive Manufacturing and 3D Printing Technologies · Cellular Mechanics and Interactions

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Zoological Institute Karlsruhe Institute of Technology (KIT) Fritz‐Haber‐Weg 4 76131 Karlsruhe Germany

Institute of Applied Physics Karlsruhe Institute of Technology (KIT) Wolfgang‐Gaede‐Str. 1 76131 Karlsruhe Germany

Institute of Functional Interfaces Karlsruhe Institute of Technology (KIT) Hermann‐von‐Helmholtz‐Platz 1 76344 Eggenstein‐Leopoldshafen Germany

Macromolecular Architectures Institute for Technical Chemistry and Polymer Chemistry Karlsruhe Institute of Technology (KIT) Engesserstr. 18 76128 Karlsruhe Germany

School of Chemistry Physics and Mechanical Engineering Queensland University of Technology (QUT) 2 George Street Brisbane QLD 4000 Australia

Institute of Nanotechnology Karlsruhe Institute of Technology (KIT) Hermann‐von‐Helmholtz‐Platz 1 76344 Eggenstein‐Leopoldshafen Germany

References (40)

Show source-provided references
1. 10.1016/j.yexcr.2015.10.03710.1016/j.yexcr.2015.10.037 ↗
2. 10.1038/nrm390410.1038/nrm3904 ↗
3. 10.1101/cshperspect.a00505810.1101/cshperspect.a005058 ↗
4. 10.1038/ncomms532410.1038/ncomms5324 ↗
5. 10.1016/j.tcb.2016.08.00810.1016/j.tcb.2016.08.008 ↗
6. 10.1146/annurev-chembioeng-062011-08094510.1146/annurev-chembioeng-062011-080945 ↗
7. 10.1016/j.biomaterials.2013.10.03810.1016/j.biomaterials.2013.10.038 ↗
8. 10.1002/smll.20160068310.1002/smll.201600683 ↗
9. 10.1016/j.gendis.2017.10.00210.1016/j.gendis.2017.10.002 ↗
10. 10.1016/j.mattod.2017.06.00410.1016/j.mattod.2017.06.004 ↗
11. 10.1039/C5CS00278H10.1039/C5CS00278H ↗
12. 10.1021/acsbiomaterials.7b0043810.1021/acsbiomaterials.7b00438 ↗
13. 10.1039/C4NR06500J10.1039/C4NR06500J ↗
14. 10.1586/erd.12.4810.1586/erd.12.48 ↗
15. Shpichka A. · 2018 · 7110.1007/978-3-319-75801-5_3 ↗
16. 10.5301/JABFM.2012.927810.5301/JABFM.2012.9278 ↗
17. 10.1002/anie.20170469510.1002/anie.201704695 ↗
18. 10.1002/adfm.20140139010.1002/adfm.201401390 ↗
19. 10.1016/j.biomaterials.2015.08.01610.1016/j.biomaterials.2015.08.016 ↗
20. 10.1002/adma.20080131910.1002/adma.200801319 ↗
21. 10.1016/j.biomaterials.2013.09.09510.1016/j.biomaterials.2013.09.095 ↗
22. 10.1002/adhm.20170088810.1002/adhm.201700888 ↗
23. 10.1016/j.mee.2018.01.00710.1016/j.mee.2018.01.007 ↗
24. 10.1002/adma.20100406010.1002/adma.201004060 ↗
25. 10.1002/adma.20160434210.1002/adma.201604342 ↗
26. 10.1002/adma.20090251510.1002/adma.200902515 ↗
27. 10.1016/j.biomaterials.2014.12.01810.1016/j.biomaterials.2014.12.018 ↗
28. 10.1016/j.bpj.2017.06.05810.1016/j.bpj.2017.06.058 ↗
29. 10.1529/biophysj.108.13429610.1529/biophysj.108.134296 ↗
30. 10.1002/smll.20170062110.1002/smll.201700621 ↗
31. 10.1088/2057-1976/aaab9310.1088/2057-1976/aaab93 ↗
32. 10.3390/ma1001006610.3390/ma10010066 ↗
33. 10.1016/j.actbio.2017.03.03910.1016/j.actbio.2017.03.039 ↗
34. 10.1016/j.actbio.2015.02.02510.1016/j.actbio.2015.02.025 ↗
35. 10.1364/BOE.6.00048010.1364/BOE.6.000480 ↗
36. 10.3390/ma401028810.3390/ma4010288 ↗
37. 10.1088/1748-6041/6/5/05500310.1088/1748-6041/6/5/055003 ↗
38. 10.1021/la402346z10.1021/la402346z ↗
39. 10.1002/adma.20170556410.1002/adma.201705564 ↗
40. 10.1038/s41467-018-08175-w10.1038/s41467-018-08175-w ↗