journal article·2013-09-14

A Triggered DNA Hydrogel Cover to Envelop and Release Single Cells

Juan Jin, Yongzheng Xing, Yanli Xi, Xueli Liu, Tao Zhou, Xinxin Ma, Zhongqiang Yang, Shutao Wang, Dongsheng Liu

Advanced Materials· Volume 25· Issue 34
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Abstract

We develop an enzyme-triggered permeable DNA hydrogel cover to envelop and release single cells in microwells. The porous structure of the DNA hydrogel allows nutrients and waste to pass through, leading to a cell viability as high as 98%. The design provides a general method to culture, monitor, and manipulate single cells, and has potential applications in cell patterning and studying cell communication.
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Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Microfluidic and Bio-sensing Technologies · RNA Interference and Gene Delivery

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References (44)

Show source-provided references
1. 10.1038/nature0140610.1038/nature01406 ↗
2. 10.1039/c1cs15057j10.1039/c1cs15057j ↗
3. 10.1038/nnano.2011.18710.1038/nnano.2011.187 ↗
4. 10.1038/3502052410.1038/35020524 ↗
5. 10.1021/ja055451410.1021/ja0554514 ↗
6. 10.1039/b822719e10.1039/b822719e ↗
7. 10.1038/asiamat.2011.14710.1038/asiamat.2011.147 ↗
8. 10.1002/anie.20040065110.1002/anie.200400651 ↗
9. 10.1002/ejic.20050042510.1002/ejic.200500425 ↗
10. 10.1038/nnano.2011.4910.1038/nnano.2011.49 ↗
11. 10.1039/c1nr10882d10.1039/c1nr10882d ↗
12. 10.1115/1.164552910.1115/1.1645529 ↗
13. 10.1021/ma047803h10.1021/ma047803h ↗
14. 10.1038/nmat174110.1038/nmat1741 ↗
15. 10.1021/ja801339w10.1021/ja801339w ↗
16. 10.1002/anie.20090253810.1002/anie.200902538 ↗
17. 10.1039/B817788K10.1039/B817788K ↗
18. 10.1002/adma.20100334310.1002/adma.201003343 ↗
19. 10.1039/c1sm05284e10.1039/c1sm05284e ↗
20. 10.1038/nnano.2012.21110.1038/nnano.2012.211 ↗
21. 10.1021/ma801414p10.1021/ma801414p ↗
22. 10.1007/s10439-008-9530-z10.1007/s10439-008-9530-z ↗
23. 10.1021/ja305109n10.1021/ja305109n ↗
24. 10.1002/smll.20070036610.1002/smll.200700366 ↗
25. 10.1002/anie.20090557010.1002/anie.200905570 ↗
26. 10.1002/anie.20070414310.1002/anie.200704143 ↗
27. 10.1021/la035129b10.1021/la035129b ↗
28. 10.1039/b603961h10.1039/b603961h ↗
29. 10.1039/b615235j10.1039/b615235j ↗
30. 10.1039/c0lc00150c10.1039/c0lc00150c ↗
31. 10.1021/ac050597710.1021/ac0505977 ↗
32. 10.1002/smll.20110102810.1002/smll.201101028 ↗
33. 10.1039/b904778f10.1039/b904778f ↗
34. 10.1586/14737159.5.5.76910.1586/14737159.5.5.769 ↗
35. 10.1016/j.biomaterials.2007.03.02310.1016/j.biomaterials.2007.03.023 ↗
36. 10.1073/pnas.060866010410.1073/pnas.0608660104 ↗
37. 10.1039/b705085m10.1039/b705085m ↗
38. 10.1002/(SICI)1521-3773(19980316)37:5<550::AID-ANIE550>3.0.CO;2-G10.1002/(SICI)1521-3773(19980316)37:5<550::AID-ANIE550>3.0.CO;2-G ↗
39. 10.1021/ar900245u10.1021/ar900245u ↗
40. 10.1073/pnas.050843210310.1073/pnas.0508432103 ↗
41. 10.1002/anie.20100585310.1002/anie.201005853 ↗
42. 10.1002/adma.20110243510.1002/adma.201102435 ↗
43. 10.1002/anie.20090166810.1002/anie.200901668 ↗
44. 10.1002/anie.20120413910.1002/anie.201204139 ↗