journal article·2018-10Open access

Tailor‐Made Functional Peptide Self‐Assembling Nanostructures

Moran Amit, Sivan Yuran, Ehud Gazit, Meital Reches, Nurit Ashkenasy

Advanced Materials· Volume 30· Issue 41

Abstract

Abstract Noncovalent interactions are the main driving force in the folding of proteins into a 3D functional structure. Motivated by the wish to reveal the mechanisms of the associated self‐assembly processes, scientists are focusing on studying self‐assembly processes of short protein segments (peptides). While this research has led to major advances in the understanding of biological and pathological process, only in recent years has the applicative potential of the resulting self‐assembled peptide assemblies started to be explored. Here, major advances in the development of biomimetic supramolecular peptide assemblies as coatings, gels, and as electroactive materials, are highlighted. The guiding lines for the design of helical peptides, β strand peptides, as well as surface binding monolayer‐forming peptides that can be utilized for a specific function are highlighted. Examples of their applications in diverse immerging applications in, e.g., ecology, biomedicine, and electronics, are described. Taking into account that, in addition to extraordinary design flexibility, these materials are naturally biocompatible and ecologically friendly, and their production is cost effective, the emergence of devices incorporating these biomimetic materials in the market is envisioned in the near future.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Supramolecular Self-Assembly in Materials · Polydiacetylene-based materials and applications · Antimicrobial Peptides and Activities

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Materials Engineering Ben Gurion University of the Negev Beer‐Sheva 84105 Israel

Department of Electrical and Computer Engineering UC San Diego La Jolla CA 92093‐0407 USA

Institute of Chemistry and The Center for Nanoscience and Nanotechnology The Hebrew University of Jerusalem Jerusalem 91904 Israel

Department of Molecular Microbiology and Biotechnology Department of Materials Science and Engineering Tel Aviv University Tel Aviv 69978 Israel

Funding

European Research Council · United States - Israel Binational Science Foundation

References (100+)

Show source-provided references
1. 10.1126/science.196219110.1126/science.1962191 ↗
2. 10.1021/ar800092610.1021/ar8000926 ↗
3. 10.1126/science.107082110.1126/science.1070821 ↗
4. 10.1039/b605536m10.1039/b605536m ↗
5. 10.1016/j.addr.2012.09.01010.1016/j.addr.2012.09.010 ↗
6. 10.1021/jacs.7b0051310.1021/jacs.7b00513 ↗
7. 10.1038/nbt87410.1038/nbt874 ↗
8. 10.1038/nnano.2017.410.1038/nnano.2017.4 ↗
9. 10.1073/pnas.78.9.527510.1073/pnas.78.9.5275 ↗
10. 10.1039/C6CS00542J10.1039/C6CS00542J ↗
11. 10.1002/adma.20150596110.1002/adma.201505961 ↗
12. 10.1021/acs.accounts.7b0029710.1021/acs.accounts.7b00297 ↗
13. 10.1088/0957-4484/27/40/40200210.1088/0957-4484/27/40/402002 ↗
14. 10.1038/nbt87410.1038/nbt874 ↗
15. 10.1002/smll.20090035810.1002/smll.200900358 ↗
16. 10.1016/S1748-0132(08)70041-010.1016/S1748-0132(08)70041-0 ↗
17. 10.1039/C4OB00447G10.1039/C4OB00447G ↗
18. 10.1002/anie.20131000610.1002/anie.201310006 ↗
19. 10.1039/c0sm01218a10.1039/c0sm01218a ↗
20. 10.1146/annurev.neuro.26.010302.08114210.1146/annurev.neuro.26.010302.081142 ↗
21. 10.1038/nature0368010.1038/nature03680 ↗
22. 10.1039/C7CS00372B10.1039/C7CS00372B ↗
23. 10.1126/science.108238710.1126/science.1082387 ↗
24. 10.1088/0957-4484/22/24/24560910.1088/0957-4484/22/24/245609 ↗
25. 10.1021/nl035159z10.1021/nl035159z ↗
26. 10.1002/anie.20100344610.1002/anie.201003446 ↗
27. 10.1039/c3tb21456g10.1039/c3tb21456g ↗
28. 10.1038/nnano.2015.2710.1038/nnano.2015.27 ↗
29. 10.1007/s13204-017-0551-510.1007/s13204-017-0551-5 ↗
30. 10.1021/ja035882r10.1021/ja035882r ↗
31. 10.1002/bip.2132810.1002/bip.21328 ↗
32. 10.1039/c2cs35172b10.1039/c2cs35172b ↗
33. 10.1021/ja104373e10.1021/ja104373e ↗
34. 10.1021/nn302983e10.1021/nn302983e ↗
35. 10.1039/c2sm26017d10.1039/c2sm26017d ↗
36. 10.1002/anie.20160483310.1002/anie.201604833 ↗
37. 10.1002/bip.2134510.1002/bip.21345 ↗
38. 10.1021/bi00481a00110.1021/bi00481a001 ↗
39. Mondal S. · Nat. Commun. · 2015 · 6
40. 10.1126/science.aaf490110.1126/science.aaf4901 ↗
41. 10.1039/C7BM00006E10.1039/C7BM00006E ↗
42. 10.1039/C5SC00560D10.1039/C5SC00560D ↗
43. 10.1002/bip.2265310.1002/bip.22653 ↗
44. 10.1021/la202247m10.1021/la202247m ↗
45. 10.1038/srep3679310.1038/srep36793 ↗
46. 10.1016/j.copbio.2015.12.01210.1016/j.copbio.2015.12.012 ↗
47. 10.1016/j.watres.2014.03.04510.1016/j.watres.2014.03.045 ↗
48. 10.1021/cr200350v10.1021/cr200350v ↗
49. 10.1016/j.biotechadv.2015.01.01310.1016/j.biotechadv.2015.01.013 ↗
50. 10.1039/C4RA17244B10.1039/C4RA17244B ↗
51. 10.1146/annurev-matsci-070511-15501210.1146/annurev-matsci-070511-155012 ↗
52. 10.1002/adma.20100121510.1002/adma.201001215 ↗
53. 10.1039/C6CC01438K10.1039/C6CC01438K ↗
54. 10.1073/pnas.120197310910.1073/pnas.1201973109 ↗
55. 10.1038/nbt.302010.1038/nbt.3020 ↗
56. 10.1042/BJ2014125110.1042/BJ20141251 ↗
57. 10.1021/ja406231b10.1021/ja406231b ↗
58. 10.1128/AAC.01254-0810.1128/AAC.01254-08 ↗
59. 10.1111/j.1365-2672.2008.03942.x10.1111/j.1365-2672.2008.03942.x ↗
60. 10.1080/0892701090295420710.1080/08927010902954207 ↗
61. 10.1002/adhm.20160075710.1002/adhm.201600757 ↗
62. 10.1016/j.biomaterials.2009.03.02510.1016/j.biomaterials.2009.03.025 ↗
63. 10.1016/j.actbio.2014.03.02610.1016/j.actbio.2014.03.026 ↗
64. 10.1016/j.actbio.2016.01.03510.1016/j.actbio.2016.01.035 ↗
65. 10.1021/acsami.5b0369710.1021/acsami.5b03697 ↗
66. 10.1021/acsami.5b1194910.1021/acsami.5b11949 ↗
67. 10.1021/la010384m10.1021/la010384m ↗
68. 10.1021/jp972635z10.1021/jp972635z ↗
69. 10.1016/j.biomaterials.2009.07.00110.1016/j.biomaterials.2009.07.001 ↗
70. 10.1039/C4CC03578J10.1039/C4CC03578J ↗
71. 10.1073/pnas.060555210310.1073/pnas.0605552103 ↗
72. 10.1126/science.212.4498.103810.1126/science.212.4498.1038 ↗
73. 10.1021/am500121310.1021/am5001213 ↗
74. 10.1016/S0921-5093(97)00806-X10.1016/S0921-5093(97)00806-X ↗
75. 10.1002/anie.20151178110.1002/anie.201511781 ↗
76. 10.1021/la300268d10.1021/la300268d ↗
77. 10.1021/la401586610.1021/la4015866 ↗
78. 10.1039/C6NR04550B10.1039/C6NR04550B ↗
79. 10.1039/C5CP00088B10.1039/C5CP00088B ↗
80. 10.1039/b906783c10.1039/b906783c ↗
81. 10.1021/nl062835z10.1021/nl062835z ↗
82. 10.1039/b819002j10.1039/b819002j ↗
83. 10.1002/smll.20090205010.1002/smll.200902050 ↗
84. 10.1021/ac050414g10.1021/ac050414g ↗
85. 10.1021/nl048418910.1021/nl0484189 ↗
86. 10.1039/C4CS00297K10.1039/C4CS00297K ↗
87. 10.1021/ja00199a04410.1021/ja00199a044 ↗
88. 10.1021/j100162a07410.1021/j100162a074 ↗
89. 10.1016/0167-4838(92)90058-L10.1016/0167-4838(92)90058-L ↗
90. 10.1021/ja029787e10.1021/ja029787e ↗
91. 10.1021/jp051592g10.1021/jp051592g ↗
92. 10.1021/la070175n10.1021/la070175n ↗
93. 10.1016/j.cbpa.2008.08.02610.1016/j.cbpa.2008.08.026 ↗
94. 10.1016/j.bioelechem.2011.11.01310.1016/j.bioelechem.2011.11.013 ↗
95. 10.1021/la302716n10.1021/la302716n ↗
96. 10.1039/C2CC16665H10.1039/C2CC16665H ↗
97. 10.1021/jacs.5b0393310.1021/jacs.5b03933 ↗
98. 10.1021/ja049469a10.1021/ja049469a ↗
99. 10.1021/jp063073z10.1021/jp063073z ↗
100. 10.1002/pola.1083310.1002/pola.10833 ↗