journal article·2001-04

Topographical Micropatterning of Poly(dimethylsiloxane) Using Laminar Flows of Liquids in Capillaries

S. Takayama, E. Ostuni, X. Qian, J. C. McDonald, X. Jiang, P. LeDuc, M.-H. Wu, D. E. Ingber, G. M. Whitesides

Advanced Materials· Volume 13· Issue 8
Publisher page

Abstract

“Micro-landscapes” suitable for investigating the behavior of living cells under different stimuli are cast from poly(dimethylsiloxane) by simultaneously etching a slab and a relief (see Figure) with a Bu4NF solution and flushing out dissolved material with N-methylpyrrolidone. It is crucial that all liquid streams during the etching process are laminar. Various accessible topographies for the relief and examples of applications are given.
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Research context

OpenAlex topics: 3D Printing in Biomedical Research · Nanofabrication and Lithography Techniques · Innovative Microfluidic and Catalytic Techniques Innovation

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